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RECOMBINANT HUMAN INTERLEUKIN-8 (77 AMINO ACIDS)

MBS232259

0.025 mg

430 USD

MBS232259

Recombinant Protein

RECOMBINANT HUMAN INTERLEUKIN-8 (77 AMINO ACIDS)

IL-8

interleukin-8; Interleukin-8; interleukin-8; T-cell chemotactic factor; alveolar macrophage chemotactic factor I; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; emoctakin; granulocyte chemotactic protein 1; interleukin 8; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; tumor necrosis factor-induced gene 1; chemokine (C-X-C motif) ligand 8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factorCleaved into the following 7 chains:MDNCF-aAlternative name(s):GCP/IL-8 protein IV; IL8/NAP1 form I

CXCL8; CXCL8; IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1; IL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF

IL8_HUMAN

99

>98% by SDS PAGE and HPLC analysis

Purified recombinant protein expressed in E Coli - lyophilised

Approximate Protein Concentration: 0.1 mg/ml

Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 3 months from date of reconstitution.

Functional Assays (FN)

Functional Assays: Minimum Dilution: 25ng/ml; Maximum Dilution: 150ng/ml

Reconstitution: Reconstitute with 0.25 ml distilled water

Target Species: Human

Human IL-8 promotes neutrophil chemotaxis and degranulation. The 77 amino acid form is the predominant form secreted by endothelial cells.

10834978

NP_000575.1

NM_000584.3

P10145

Protein Molecular Weight: 8.9kD (77 amino acid sequence)

ATF-2 Transcription Factor Network Pathway 138006!!ATF4 Activates Genes Pathway 530772!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Bladder Cancer Pathway 83115!!Bladder Cancer Pathway 527!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Chagas Disease (American Trypanosomiasis) Pathway 147809

The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]

0.025 mg

430 USD