catalog number :
MBS232221
products type :
Recombinant Protein
products full name :
RECOMBINANT CHICKEN INTERLEUKIN-1 BETA
products short name :
IL-1 BETA
other names :
interleukin-1 beta; interleukin-1 beta; IL-1 beta; interleukin 1, beta
other gene names :
IL1B; IL1beta; IL-1BETA
purity :
>85% by Ni chelate Chromatography
form :
Rec. Protein. Purified His-tagged recombinant protein expressed in E Coli - liquid
concentration :
Approximate Protein Concentration: 250 ug/ml
storage stability :
Store at -20 degree C only. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 3 months from date of despatch.
tested application :
Functional Assays (FN), In Vitro Assay (IA)
other info1 :
Preparation: Recombinant protein prepared from E Coli
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Chicken
products description :
Interleukin-1 (IL-1) is a pro-inflammatory cytokine secreted by many different cell types which acts upon a wide range of target cells, resulting in a diverse range of effects. The biological properties of IL-1 include the induction of B cell proliferation, stimulation of T cell proliferation in conjunction with IL-2 and the production of collagenase and prostaglandin by fibroblasts. IL-1 is also responsible for triggering the acute-phase response in the liver, and is involved in both cytokine network and vascular endothelium activation. MBS232221 induces corticosterone secretion in vivo, see Weining, K.C. et al. for details. MBS232221 is also the immunogen used to produce MyBioSource chicken IL-1beta antibody product code MBS220072.
ncbi acc num :
NP_989855.1
ncbi gb acc num :
NM_204524.1
ncbi mol weight :
Protein Molecular Weight: approximately 23kD
ncbi pathways :
Apoptosis Pathway (83966); Apoptosis Pathway (470); Cytokine-cytokine Receptor Interaction Pathway (119307); Cytokine-cytokine Receptor Interaction Pathway (460); Cytosolic DNA-sensing Pathway (125152); Cytosolic DNA-sensing Pathway (124833); Herpes Simplex Infection Pathway (377875); Herpes Simplex Infection Pathway (377865); Influenza A Pathway (217175); Influenza A Pathway (217150)