This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
protein
product name :
SYNTHETIC HUMAN OSTEOPONTIN
catalog :
MBS230361
quantity :
0.05 mg
price :
205 USD
product information
catalog number :
MBS230361
products type :
Purified Protein
products full name :
SYNTHETIC HUMAN OSTEOPONTIN
products short name :
OSTEOPONTIN
other names :
osteopontin isoform OPN-b; Osteopontin; osteopontin; SPP1/CALPHA1 fusion; early T-lymphocyte activation 1; nephropontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); urinary stone protein; uropontin; secreted phosphoprotein 1; Bone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin
other gene names :
SPP1; SPP1; OPN; BNSP; BSPI; ETA-1; BNSP; OPN; SPP-1
uniprot entry name :
OSTP_HUMAN
sequence length :
300
sequence :
I-P-V-K-Q-A-D-S-G-S-S(-C)
purity :
HPLC: >95%
form :
Purified. Purified synthetic peptide - lyophilised
storage stability :
At -20 degree C after reconstitution. Shelf Life: 6 months from the date of despatch.
tested application :
ELISA (EIA)
other info1 :
Reconstitution: Use sterile DI water or a physiological buffer of choice. Preparation: Solid phase synthesis
other info2 :
Buffer Solution: Acetate salt. Target Species: Human
products description :
Synthetic human Osteopontin also known as Bone sialoprotein 1, nephropontin, secreted phosphoprotein 1, urinary stone protein or uropontin is a peptide corresponding to amino acids 17-27 of native human osteopontin, itself a 314 amino acid (including a 16 amino acid N-terminal signal peptide) multifunctional glycoprotein highly expressed in bone and a number of cell types including macrophages, endothelial and smooth muscle cells (Mazzali et al. 2002). The N-terminal peptide sequence for synthetic osteopontin is present in all five isoforms of human osteopontin described (UniProt: P10451). Polymorphisms in the osteopontin gene appear to contribute to susceptibility to systemic lupus erythematosus (D'Alfonso et al. 2005) and elevation of serum osteopontin levels correlate with disease severity in these patients (Wong et al. 2005).
ncbi gi num :
4759166
ncbi acc num :
NP_000573.1
ncbi gb acc num :
NM_000582.2
uniprot acc num :
P10451
ncbi mol weight :
1.2 kD
ncbi pathways :
BDNF Signaling Pathway 712093!!Degradation Of The Extracellular Matrix Pathway 576263!!Direct P53 Effectors Pathway 137939!!ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479!!Endochondral Ossification Pathway 198812!!Extracellular Matrix Organization Pathway 576262!!FGF Signaling Pathway 137989!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067
ncbi summary :
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
size :
0.05 mg
price :
205 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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