catalog number :
MBS230295
products type :
Purified Protein
products full name :
PURIFIED HUMAN ALBUMIN
products short name :
SERUM ALBUMIN
other names :
serum albumin preproprotein; Serum albumin; serum albumin; albumin (32 AA); albumin (AA 34); cell growth inhibiting protein 42; growth-inhibiting protein 20; albumin
other gene names :
ALB; ALB; FDAH; ANALBA; PRO0883; PRO0903; PRO1341
uniprot entry name :
ALBU_HUMAN
purity :
>99% by SDS PAGE
form :
Purified. Purified human serum albumin - liquid
concentration :
Total protein concentration 1.0 mg/ml
storage stability :
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 6 months from date of despatch.
tested application :
Immunoassay (IY)
other info1 :
Perservative Stabilisers: None present. For long term storage the addition of 0.09% sodium azide is recommended. N.B. For functional studies do not add sodium azide. Preparation: Purified albumin from human urine.
other info2 :
Buffer Solution: Ammonium bicarbonate. Target Species: Human. Health and Safety Information: Donor material tested and found negative for HIV1 and 2 antibodies, HBsAg and HCV antibodies.
products description :
MBS230295, human albumin, is a 66 kDa protein that binds and transports steroids, fatty acids, metal ions and thyroid hormones. Albumin accounts for approximately 50% of blood serum protein.
ncbi acc num :
NP_000468.1
ncbi gb acc num :
NM_000477.5
ncbi pathways :
Bile Acid And Bile Salt Metabolism Pathway (106144); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); HDL-mediated Lipid Transport Pathway (106158); Hemostasis Pathway (106028); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Platelet Activation, Signaling And Aggregation Pathway (106034)
ncbi summary :
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
uniprot summary :
albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted; Carrier. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; protein complex; extracellular region; basement membrane; nucleus. Molecular Function: antioxidant activity; toxin binding; protein binding; enzyme binding; copper ion binding; DNA binding; zinc ion binding; chaperone binding; drug binding; oxygen binding; fatty acid binding; pyridoxal phosphate binding. Biological Process: receptor-mediated endocytosis; platelet activation; sodium-independent organic anion transport; maintenance of mitochondrion localization; bile acid metabolic process; lipoprotein metabolic process; hemolysis by symbiont of host red blood cells; cellular response to starvation; response to mercury ion; bile acid and bile salt transport; response to organic substance; retinal homeostasis; platelet degranulation; transport; negative regulation of programmed cell death; blood coagulation; transmembrane transport; positive regulation of circadian sleep/wake cycle, non-REM sleep; response to nutrient; negative regulation of apoptosis. Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic