catalog number :
MBS230287
products type :
Purified Protein
products full name :
HUMAN IgG2 KAPPA
products short name :
IgG2
other names :
Ig gamma-2 chain C region, partial; Ig gamma-2 chain C region; immunoglobulin heavy constant gamma 2 (G2m marker)
products gene name :
IgG2 KAPPA
other gene names :
IGHG2; IGHG2
uniprot entry name :
IGHG2_HUMAN
form :
Purified. Purified protein - liquid
concentration :
Approximate Protein Concentrations: 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA)
other info1 :
Perservative Stabilisers: 0.1% Sodium Azide. 0.1% EACA. 0.01% Benzamidine. Preparation: Purified protein prepared from human myeloma serum by ion exchange chromatography, gel filtration and protein A chromatography.
other info2 :
Buffer Solution: TRIS buffered saline. Target Species: Human. External Database Links: UniProt: . P01834. P01859. Entrez Gene:. 3514 IGKC. 3501 IGHG2. Health and Safety Information: Donor material tested and found negative for HBsAg and antibodies to HIV and HCV. As no test can completely guarantee this material to be free of pathogens it should be handled as potentially infectious.
ncbi mol weight :
35,901 Da
ncbi pathways :
Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); FCGR Activation Pathway (771578); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway (771579); Role Of Phospholipids In Phagocytosis Pathway (771580)
uniprot summary :
IGHG2: . Protein type: Immunoglobulin superfamily. Chromosomal Location of Human Ortholog: 14q32.33. Cellular Component: extracellular space; extracellular region. Molecular Function: protein binding; antigen binding. Biological Process: innate immune response; complement activation, classical pathway; complement activation