product summary
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company name :
MyBioSource
product type :
protein
product name :
NATIVE HUMAN CD71
catalog :
MBS230246
quantity :
0.02 mg
price :
295 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS230246
products type :
Purified Protein
products full name :
NATIVE HUMAN CD71
products short name :
CD71
other names :
transferrin receptor protein 1; Transferrin receptor protein 1; transferrin receptor protein 1; transferrin receptor (p90, CD71); transferrin receptor; T9; p90; CD_antigen: CD71Transferrin receptor protein 1, serum form; sTfR
products gene name :
CD71
other gene names :
TFRC; TFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR; TR; TfR; TfR1; Trfr; sTfR
uniprot entry name :
TFR1_HUMAN
sequence length :
760
purity :
>90%
form :
Purified
concentration :
Total protein concentration 0.1mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch.
tested application :
ELISA (EIA)
app notes :
Western Blot: Purified protein from human placenta - liquid
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Human
ncbi gi num :
189458819
ncbi acc num :
NP_001121620.1
ncbi gb acc num :
NM_001128148.1
uniprot acc num :
P02786
ncbi mol weight :
On SDS-PAGE a band corresponding to the Transferrin receptor dimer, molecular weight of 180 kDa, is visible along with higher polymers. On reduction with mercaptoethanol, a single band at 90 kDa is visible.
ncbi pathways :
Clathrin Derived Vesicle Budding Pathway (119545); Endocytosis Pathway (102279); Endocytosis Pathway (102181); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Golgi Associated Vesicle Biogenesis Pathway (119546); HIF-1 Signaling Pathway (695200); HIF-1-alpha Transcription Factor Network Pathway (138045); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Iron Metabolism In Placenta Pathway (672461)
uniprot summary :
TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Protein type: Receptor, misc.; Membrane protein, integral; Cell surface. Chromosomal Location of Human Ortholog: 3q29. Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; integral to plasma membrane; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; membrane; perinuclear region of cytoplasm; plasma membrane; melanosome; endosome; vesicle; external side of plasma membrane. Molecular Function: identical protein binding; protein binding; transferrin receptor activity; double-stranded RNA binding. Biological Process: receptor-mediated endocytosis; viral reproduction; cellular iron ion homeostasis; transferrin transport; positive regulation of bone resorption; regulation of cell growth; osteoclast differentiation; transmembrane transport; regulation of cell proliferation
size1 :
0.02 mg
price1 :
295 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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