catalog number :
MBS230101
products type :
Purified Protein
products full name :
NATIVE BOVINE CALMODULIN
products short name :
CALMODULIN
other names :
calmodulin; Calmodulin; calmodulin; calmodulin 3 (phosphorylase kinase, delta)
other gene names :
CALM3; CALM; CAM; CaM
uniprot entry name :
CALM_BOVIN
purity :
> 95%. Determined by SDS-PAGE.
form :
Purified. Purified calmodulin from bovine brain - lyophilised
storage stability :
Prior to reconstitution store at -20 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Shelf Life: 12 months from date of reconstitution.
tested application :
ELISA (EIA)
other info1 :
Reconstitution: Reconstitute to a concentration of 0.1 - 1 mg/ml in distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution. Perservative Stabilisers: 2 mM EDTA. Preparation: Purified by ion-exchange chromatography followed by gel-filtration.
other info2 :
Activity: More than 40,000 units per 1 mg of protein.One unit will stimulate 0.016 activated units of phosphodiesterase, 3'5'-cyclic nucleotide, P 0520, to 50% of the maximum activity of the enzyme when saturated with activator. Target Species: Bovine
products description :
Calmodulin is a ubiquitous 16.6 kDa protein found in all eukaryote cells that is involved with the control of a large number of calcium sensitive enzymes. It can bind to and regulate a number of different protein targets, thereby affecting many different cellular functions.
ncbi acc num :
NP_001039714.1
ncbi gb acc num :
NM_001046249.2
ncbi mol weight :
16,838 Da
ncbi pathways :
Activation Of Ca-permeable Kainate Receptor Pathway (1120489); Activation Of CaMK IV Pathway (1120485); Activation Of Kainate Receptors Upon Glutamate Binding Pathway (1120486); Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (1120476); Adaptive Immune System Pathway (1119287); Adrenergic Signaling In Cardiomyocytes Pathway (908260); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Alcoholism Pathway (585567); Alcoholism Pathway (587116); Alzheimer's Disease Pathway (84336)
uniprot summary :
Calmodulin: a calcium-binding small regulatory protein that mediates the control of a large number of enzymes by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Has four functional calcium-binding domains. Phosphorylation and ubiquitination result in a decreased activity. Protein type: Calcium-binding