catalog number :
MBS224820
products full name :
MOUSE ANTI PIG IgA
products short name :
[IgA]
other names :
[IgA, partial]
products gene name :
[IgA]
purity :
Purified IgG- liquid
concentration :
1.0 mg/ml
storage stability :
Store at +4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology- Frozen, ELISA, Flow Cytometry
app notes :
ELISA: 1/50K - 1/500K
other info1 :
Target Species: Pig. Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant. Preservative Stabilisers: 0.09% Sodium Azide (NaN 3 ). Buffer Solution: Phosphate buffered saline.
other info2 :
Immunogen: Porcine IgA. Fusion Partners: Spleen cells from immunised mice were fused with cells of the mouse P3-X63-Ag8.653 myeloma cell line.
products description :
Mouse Anti Pig IgA antibody, clone K61 1B4 recognizes porcine immunoglobulin (Ig) alpha chain. No cross-reactivity is observed with either porcine IgM or IgG.It has been suggested that pigs possess two subclasses of IgA, referred to as either IgA1 and IgA2 similar to the human IgA subclasses. More recent research indicates that these are allotypic variants and described as IgAa and IgAb (Navarro et al. 2000). Research undertaken in connection with porcine IgA response to Foot and Mouth disease (Pacheco et al. 2010) has demonstrated that clone K61 1B4 recognises both IgAa and IgAb allotypes.IgA is the dominant immunoglobulin found in surface secretions where its role is in the protection of body surfaces. High levels of IgA may be detected in tracheal secretions, saliva, intestinal fluid and urogenital tract secretions. The primary function of IgA is to prevent adherence of bacteria and virus to epithelial surfaces. IgA may also act within epithelial cells where it has a role in interrupting viral replication.
ncbi acc num :
CAA10818.1