antibody

SHEEP ANTI HUMAN ALPHA 1 MICROGLOBULIN:HRP

MBS223921

1 mL

390 USD

polyclonal

sheep

HRP

ELISA, enzyme immunoassay

Antibody

SHEEP ANTI HUMAN ALPHA 1 MICROGLOBULIN:HRP

ALPHA 1 MICROGLOBULIN

protein AMBP preproprotein; Protein AMBP; protein AMBP; bikunin; complex-forming glycoprotein heterogeneous in charge; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; protein HC; trypstatin; uristatin; uronic-acid-rich protein; alpha-1-microglobulin/bikunin precursor; Alpha-1 microglycoprotein; Complex-forming glycoprotein heterogeneous in charge

AMBP; AMBP; A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC; HCP; ITIL; Protein HC; ITI-LC

AMBP_HUMAN

Polyclonal

IgG

Sheep

352

HRP. Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid

IgG concentration 1mg/ml

Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

Immunohistology Frozen, ELISA (EIA)

Immunohistology - Frozen: Minimum Dilution: 1/10; Maximum Dilution: 1/500;. ELISA: Minimum Dilution: 1/50; Maximum Dilution: 1/300

Perservative Stabilisers: 0.01% Thiomersal. HRP Stabiliser. Preparation: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Highly pure Human alpha-1-microglobulin, prepared from the urine of patients with chronic renal proteinuria. Buffer Solution: Phosphate buffered saline. Target Species: Human

Sheep anti Human alpha 1 microglobulin antibody recognizes human alpha 1 microglobulin. Sheep anti Human alpha 1 microglobulin antibody does not demonstrate any cross reactivity with urine albumin, retinol binding protein or beta-2 microglobulin in performed testing.

4502067

NP_001624.1

NM_001633.3

P02760

38,999 Da

Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Scavenging Of Heme From Plasma Pathway (771600)

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]

AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 9q32-q33. Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; extracellular region; plasma membrane. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protein homodimerization activity; IgA binding; calcium oxalate binding; heme binding; calcium channel inhibitor activity. Biological Process: receptor-mediated endocytosis; negative regulation of JNK cascade; viral reproduction; heme catabolic process; negative regulation of immune response; protein catabolic process; female pregnancy; cell adhesion; protein-chromophore linkage

1 mL

390 USD