antibody

RABBIT ANTI WNV CORE PROTEIN (C-TERMINAL)

MBS223747

0.1 mg

365 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, immunocytochemistry, enzyme immunoassay

Antibody

RABBIT ANTI WNV CORE PROTEIN (C-TERMINAL)

WNV

unnamed protein product; Genome polyprotein; polyprotein precursor; capsid protein C; anchored capsid protein C; membrane glycoprotein precursor prM; membrane glycoprotein M; envelope protein E; nonstructural protein NS1; nonstructural protein NS2A; nonstructural protein NS2B; nonstructural protein NS3; nonstructural protein NS4A; 2K protein; nonstructural protein NS4B; nonstructural protein NS5; Core protein

WNV

WNVgp1; NS1; NS2A; NS4A; NS4B

POLG_WNV

Polyclonal

IgG

Rabbit

3430

This item recognises the 14kDa core protein of West Nile Virus (WNV). WNV belongs to the Flaviviridae family which includes closely viruses such as Dengue fever, Yellow fever and Tick borne encephalitis. West Nile Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope containing envelope and matrix proteins. Research indicates that the viral core protein contributes to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway. West Nile Virus is spread by mosquitos and is believed to have originated in the West Nile region of Africa but has now spread to Europe, Asia and America where it has become a significant disease affecting human and domestic animal health.

Purified. Purified IgG - liquid

IgG concentration 1.0mg/ml

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)

Western Blot: This item detects a band of approximately 14kDa in Transfected HeLa cell lysate. ELISA: Maximum Dilution: 1ug/ml. Immunofluorescence: Maximum Dilution: 20ug/ml. Western Blotting: Maximum Dilution: 1ug/ml

Perservative Stabilisers: 0.02% Sodium Azide (NaN3)

Immunogen: A peptide corresponding to an 15 amino acid sequence from near the carboxy terminus of West Nile Virus core protein. Buffer Solution: Phosphate buffered saline. Antiserum Preparation: Antiserum to human West Nile Virus core protein was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Viral

MBS223747 recognises the 14kDa core protein of West Nile Virus (WNV). WNV belongs to the Flaviviridae family which includes closely viruses such as Dengue fever, Yellow fever and Tick borne encephalitis. West Nile Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope containing envelope and matrix proteins. Research indicates that the viral core protein contributes to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway. West Nile Virus is spread by mosquitos and is believed to have originated in the West Nile region of Africa but has now spread to Europe, Asia and America where it has become a significant disease affecting human and domestic animal health.

11528014

NP_041724.2

NC_001563.2

P06935

380,110 Da

0.1 mg

365 USD