GOAT ANTI HUMAN KINESIN HEAVY CHAIN (C-TERMINAL) | MyBioSource MBS222873 product information

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product summary

company name :

MyBioSource

product type :

antibody

product name :

GOAT ANTI HUMAN KINESIN HEAVY CHAIN (C-TERMINAL)

catalog :

MBS222873

quantity :

0.1 mg

price :

500 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, dog

application :

western blot, ELISA, enzyme immunoassay

product information

catalog number :

MBS222873

products type :

Antibody

products full name :

GOAT ANTI HUMAN KINESIN HEAVY CHAIN (C-TERMINAL)

products short name :

KINESIN HEAVY CHAIN

other names :

kinesin-1 heavy chain; Kinesin-1 heavy chain; kinesin-1 heavy chain; conventional kinesin heavy chain; epididymis secretory protein Li 61; kinesin 1 (110-120kD); ubiquitous kinesin heavy chain; kinesin family member 5B; Conventional kinesin heavy chain; Ubiquitous kinesin heavy chain; UKHC

other gene names :

KIF5B; KIF5B; KNS; KINH; KNS1; UKHC; HEL-S-61; KNS; KNS1; UKHC

uniprot entry name :

KINH_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Goat

reactivity :

Dog (Expected from Sequence)

sequence length :

963

form :

Purified. Purified IgG - liquid

concentration :

IgG concentration 0.5mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)

app notes :

Western Blot: This item detects a band of approximately 120kDa in human kidney cell lysates. ELISA: Maximum Dilution: 1/32,000. Immunohistology - Paraffin: Minimum Dilution: 1.0; Maximum Dilution: 2.0ug/ml; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. . Western Blotting: Minimum Dilution: 0.2; Maximum Dilution: 1.0ug/ml

other info1 :

Perservative Stabilisers: 0.02% Sodium Azide (NaN3). 0.5% Bovine Serum Albumin

other info2 :

Histology Positive Control Tissue: Human kidney. Buffer Solution: TRIS buffered saline. Antiserum Preparation: Antiserum to human kinesin heavy chain (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human

products description :

Goat anti Human Kinesin heavy chain antibodyrecognizes the heavy chain of human kinesin, also known as Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain or KIF5B. Kinesin heavy chain is a 963 amino acid microtubule dependent motor containing a kinesin motor domain. otherwise known as, a member of the kinesin-like protein family and principal component of kinesin, involved in the plus end-directed transport of eukaryotic cell vesicles and organelles. Goat anti human kinesin heavy chain antibody binds to an epitope within the C-terminal (CT) region of human kinesin heavy chain (KHC), Kinesins are microtubule associated motor proteins which consist of 2 identical (60-70kDa) light chains and 2 identical (110-120kDa) heavy chains, the latter of which contain a globular C-terminal tail domain, a central alpha helical rod domain and a globular N-terminal motor domain with microtubule-stimulated ATPase activity.

ncbi gi num :

4758648

ncbi acc num :

NP_004512.1

ncbi gb acc num :

NM_004521.2

uniprot acc num :

P33176

ncbi mol weight :

109,685 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Dopaminergic Synapse Pathway (469199); Dopaminergic Synapse Pathway (469185); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (187196); Hemostasis Pathway (106028); Immune System Pathway (106386); Insulin Signaling Pathway (198845); Insulin Processing Pathway (105903); Kinesins Pathway (187197); MHC Class II Antigen Presentation Pathway (645290)

uniprot summary :

KIF5B: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Belongs to the kinesin-like protein family. Kinesin subfamily. Protein type: Motor; Microtubule-binding. Chromosomal Location of Human Ortholog: 10p11.22. Cellular Component: ciliary rootlet; microtubule; kinesin complex; neuron projection; membrane; perinuclear region of cytoplasm; endocytic vesicle; cytoplasm; microtubule organizing center; vesicle. Molecular Function: protein binding; plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; microtubule motor activity; ATP binding. Biological Process: axon guidance; regulation of membrane potential; cellular protein metabolic process; positive regulation of potassium ion transport; vesicle transport along microtubule; positive regulation of synaptic transmission, GABAergic; cytoplasm organization and biogenesis; cytoskeleton-dependent intracellular transport; microtubule-based movement

size1 :

0.1 mg

price1 :

500 USD