This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
RABBIT ANTI CATENIN BETA
catalog :
MBS222501
quantity :
0.05 ml
price :
780 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, dog
application :
western blot, ELISA, immunoprecipitation, enzyme immunoassay
product information
catalog number :
MBS222501
products type :
Antibody
products full name :
RABBIT ANTI CATENIN BETA
products short name :
CATENIN
other names :
catenin beta-1; Catenin beta-1; catenin beta-1; catenin (cadherin-associated protein), beta 1, 88kDa; Beta-catenin
other gene names :
CTNNB1; CTNNB1; CTNNB; MRD19; armadillo; CTNNB
uniprot entry name :
CTNB1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Dog, Mouse
sequence length :
781
specificity :
This item recognises catenin-beta, a cytosolic protein which forms complexes with cadherins and with axin (part of the Wnt signalling pathway). Catenins are present in both developing and adult tissues.
form :
Serum. Serum - liquid
storage stability :
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, ELISA (EIA), Immunoblotting (IB), Immunoprecipitation (IP), Immunohistology Paraffin*
app notes :
Immunohistology - Paraffin: Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
other info2 :
Immunogen: GST-labelled full length recombinant beta-catenin . Target Species: Human
products description :
MBS222501 recognises catenin-beta, a cytosolic protein which forms complexes with cadherins and with axin (part of the Wnt signalling pathway). Catenins are present in both developing and adult tissues.
ncbi gi num :
148233338
ncbi acc num :
NP_001091679.1
ncbi gb acc num :
NM_001098209.1
uniprot acc num :
P35222
ncbi mol weight :
9,501 Da
ncbi pathways :
AMER1 Mutants Destabilize The Destruction Complex Pathway 1127621!!APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway 1127616!!APC Truncation Mutants Have Impaired AXIN Binding Pathway 1127617!!AXIN Missense Mutants Destabilize The Destruction Complex Pathway 1127620!!AXIN Mutants Destabilize The Destruction Complex, Activating WNT Signaling Pathway 1127618!!Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Adherens Junctions Interactions Pathway 119533!!Adipogenesis Pathway 198832!!Androgen Receptor Signaling Pathway 198806
ncbi summary :
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
size :
0.05 ml
price :
780 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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