This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
RABBIT ANTI ATR (aa2122-2380)
catalog :
MBS222383
quantity :
0.1 ml
price :
455 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, cow
application :
western blot
product information
catalog number :
MBS222383
products type :
Antibody
products full name :
RABBIT ANTI ATR (aa2122-2380)
products short name :
ATR
other names :
serine/threonine-protein kinase ATR; Serine/threonine-protein kinase ATR; serine/threonine-protein kinase ATR; FRAP-related protein-1; MEC1, mitosis entry checkpoint 1, homolog; ataxia telangiectasia and Rad3-related protein; ATR serine/threonine kinase; Ataxia telangiectasia and Rad3-related protein; FRAP-related protein 1
products gene name :
ATR
other gene names :
ATR; ATR; FRP1; MEC1; SCKL; FCTCS; SCKL1; FRP1
uniprot entry name :
ATR_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Bovine, Hamster, Mouse
sequence length :
2644
specificity :
This item recognises the ATR (Ataxia telangiectasia and rad 3 related) protein, a 300kD protein kinase reported to have a role in recognising and responding to DNA strand interruptions during meiosis.
form :
Serum. Serum - liquid
storage stability :
Store at 4 degree C for one month or at -20 degree C for longer. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Western Blot (WB)
app notes :
Western Blotting: Maximum Dilution: 1/2000
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide
other info2 :
Immunogen: Human ATR peptide, amino acids 2122-2380. Antiserum Preparation: Antisera to human ATR peptide were raised by repeated immunisation of rabbits with highly purified antigen. Target Species: Human
products description :
MBS222383 recognises the ATR (Ataxia telangiectasia and rad 3 related) protein, a 300kD protein kinase reported to have a role in recognising and responding to DNA strand interruptions during meiosis.
ncbi gi num :
157266317
ncbi acc num :
NP_001175.2
ncbi gb acc num :
NM_001184.3
uniprot acc num :
Q13535
ncbi mol weight :
297,479 Da
ncbi pathways :
Activation Of ATR In Response To Replication Stress Pathway 105754!!BARD1 Signaling Events Pathway 137959!!Cell Cycle Pathway 530733!!Cell Cycle Checkpoints Pathway 105739!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054!!Cell Cycle Pathway 463!!Cellular Response To Heat Stress Pathway 1127553!!Cellular Responses To Stress Pathway 645258!!Circadian Rhythm Pathway 137978
ncbi summary :
The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008]
size :
0.1 ml
price :
455 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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