product summary
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company name :
MyBioSource
product type :
antibody
product name :
GOAT ANTI HUMAN CHOLINE ACETYLTRANSFERASE
catalog :
MBS222195
quantity :
0.05 mL
price :
910 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS222195
products type :
Antibody
products full name :
GOAT ANTI HUMAN CHOLINE ACETYLTRANSFERASE
products short name :
CHOLINE ACETYLTRANSFERASE
other names :
choline O-acetyltransferase isoform 1; Choline O-acetyltransferase; choline O-acetyltransferase; acetyl CoA:choline O-acetyltransferase; choline acetylase; choline O-acetyltransferase
other gene names :
CHAT; CHAT; CMS1A; CMS1A2; CHOACTASE; CHOACTase; ChAT; Choline acetylase
uniprot entry name :
CLAT_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Goat
reactivity :
Guinea Pig, Mouse, Rat
sequence length :
630
specificity :
This item recognizes Choline acetyl transferase (ChAT), present in cholinergic neurons in the brain and central nervous system.
form :
Serum. Serum - liquid
storage stability :
At -20 degree C only (ship 4 degree C). Shelf Life: 12 months from date of despatch.
tested application :
Immunohistology Frozen, Western Blot (WB)
app notes :
Immunohistology - Frozen: Minimum Dilution: 1/500; Maximum Dilution: 1/1000;. Western Blotting: Minimum Dilution: 1/1000; Maximum Dilution: 1/5000
other info2 :
Immunogen: Human placental enzyme. Target Species: Human
products description :
MBS222195 recognizes Choline acetyl transferase (ChAT), present in cholinergic neurons in the brain and central nervous system.
ncbi gi num :
218931221
ncbi acc num :
NP_001136401.1
ncbi gb acc num :
NM_001142929.1
uniprot acc num :
P28329
ncbi mol weight :
70,394 Da
ncbi pathways :
Acetylcholine Neurotransmitter Release Cycle Pathway (106525); Acetylcholine Synthesis Pathway (198820); Biogenic Amine Synthesis Pathway (198793); Cholinergic Synapse Pathway (217716); Glycerophospholipid Biosynthesis Pathway (645313); Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Neuronal System Pathway (106513)
ncbi summary :
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
uniprot summary :
CHAT: an enzyme that catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Four alternative splice variants have been described. Protein type: EC 2.3.1.6; Acetyltransferase; Lipid Metabolism - glycerophospholipid. Chromosomal Location of Human Ortholog: 10q11.2. Cellular Component: cell soma; mitochondrion; axon; cytoplasm; cytosol; nucleus. Molecular Function: choline O-acetyltransferase activity. Biological Process: synaptic transmission; rhythmic excitation; rhythmic behavior; muscle development; phospholipid metabolic process; neurotransmitter secretion; glycerophospholipid biosynthetic process; phosphatidylcholine biosynthetic process; dendrite development; neuromuscular synaptic transmission; establishment of synaptic specificity at neuromuscular junction; adult walking behavior; neurotransmitter biosynthetic process. Disease: Myasthenic Syndrome, Congenital, Associated With Episodic Apnea
size1 :
0.05 mL
price1 :
910 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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