This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
RABBIT ANTI GluR1 (pSer831)
catalog :
MBS221804
quantity :
0.15 ml
price :
705 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, chicken
application :
western blot
product information
catalog number :
MBS221804
products type :
Antibody
products full name :
RABBIT ANTI GluR1 (pSer831)
products short name :
GluR1
other names :
glutamate receptor 1; Glutamate receptor 1; glutamate receptor 1; AMPA-selective glutamate receptor 1; GluR1; gluR-1; gluR-K1; glutamate receptor A; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA1 (alpha 1); glutamate receptor, ionotropic, AMPA 1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; GluA1
products gene name :
GluR1
other gene names :
Gria1; Gria1; GluA1; gluR-A; Glur1; GluR-1; GluA1
uniprot entry name :
GRIA1_RAT
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Chicken (Expected from Sequence), Dog (Expected from Sequence), Human (Expected from Sequence), Mouse (Expected from Sequence)
sequence length :
907
specificity :
This antibody is specific for rat glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831. GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses. Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.
form :
Purified. Purified IgG - liquid
storage stability :
Store at 4 degree C or -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch.
tested application :
Western Blot (WB)*
app notes :
Western Blot: This item detects a band of approximately 100 kDa in rat brain lysates. Western Blotting: Maximum Dilution: 1/1000; Application Note: For the detection of phosphoproteins, serine phosphatase inhibitors such as 10mM Sodium Fluoride should be added to the sample buffer. Milk or other casein-based blocking solutions are not recommended as casein is a phosphoprotein and its use can result in high background.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. 0.01% Bovine Serum Albumin. 50% Glycerol
other info2 :
Immunogen: Synthetic phosphopeptide corresponding to amino acid sequence within GluR1 which includes phosphorylated Ser831. Buffer Solution: 10mM HEPES pH7.5. Antiserum Preparation: Antisera to phosphorylated GluR1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by sequential affinity chromatography on phospho- and dephosphopeptide affinity columns. Target Species: Rat
products description :
This antibody is specific for rat glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831. GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses. Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.
ncbi gi num :
29789269
ncbi acc num :
NP_113796.1
ncbi gb acc num :
NM_031608.1
uniprot acc num :
P19490
ncbi mol weight :
101,555 Da
ncbi pathways :
Amphetamine Addiction Pathway 547642!!Amphetamine Addiction Pathway 550546!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83491!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511!!Circadian Entrainment Pathway 698787!!Circadian Entrainment Pathway 699872!!Dopaminergic Synapse Pathway 469193!!Dopaminergic Synapse Pathway 469185!!Glutamatergic Synapse Pathway 213815!!Glutamatergic Synapse Pathway 213811
ncbi summary :
mouse homolog may play a role in regulation of neuronal synaptic plasticity and conditioned reinforcement learning [RGD, Feb 2006]
size :
0.15 ml
price :
705 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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