GOAT ANTI HUMAN TRANSFERRIN | MyBioSource MBS221751 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

GOAT ANTI HUMAN TRANSFERRIN

catalog :

MBS221751

quantity :

1 mg

price :

235 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS221751

products type :

Antibody

products full name :

GOAT ANTI HUMAN TRANSFERRIN

products short name :

TRANSFERRIN

other names :

serotransferrin; Serotransferrin; serotransferrin; beta-1 metal-binding globulin; siderophilin; transferrin; Beta-1 metal-binding globulin; Siderophilin

other gene names :

TF; TF; TFQTL1; PRO1557; PRO2086; Transferrin

uniprot entry name :

TRFE_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Goat

sequence length :

698

form :

Purified. Purified IgG - liquid

concentration :

IgG concentration 1.0 mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

ELISA (EIA)

app notes :

ELISA: Minimum Dilution: 1/100; Maximum Dilution: 1/10,000

other info1 :

Perservative Stabilisers: 0.09% Sodium Azide

other info2 :

Immunogen: Purified human transferrin. Buffer Solution: Phosphate buffered saline. Antiserum Preparation: Antisera to human transferrin were raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human

products description :

Goat anti Human Transferrin antibody recognizes human transferrin, an iron binding glycoprotein of 79kD. Transferrin has an important role in transporting iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body

ncbi gi num :

4557871

ncbi acc num :

NP_001054.1

ncbi gb acc num :

NM_001063.3

uniprot acc num :

P02787

ncbi mol weight :

77,064 Da

ncbi pathways :

EPHB Forward Signaling Pathway (138047); HIF-1 Signaling Pathway (695200); HIF-1-alpha Transcription Factor Network Pathway (138045); Hemostasis Pathway (106028); Iron Metabolism In Placenta Pathway (672461); Iron Uptake And Transport Pathway (187191); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050)

ncbi summary :

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]

uniprot summary :

TF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Defects in TF are the cause of atransferrinemia (ATRAF). Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Belongs to the transferrin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3q22.1. Cellular Component: extracellular space; cell surface; cytoplasmic membrane-bound vesicle; early endosome; extracellular region; coated pit; recycling endosome; perinuclear region of cytoplasm; endocytic vesicle; late endosome; apical plasma membrane; basal plasma membrane; endosome membrane; vesicle. Molecular Function: protein binding; ferric iron binding; ubiquitin protein ligase binding. Biological Process: retinal homeostasis; platelet activation; platelet degranulation; cellular iron ion homeostasis; transferrin transport; blood coagulation; transmembrane transport. Disease: Atransferrinemia

size1 :

1 mg

price1 :

235 USD

more info or order :

MyBioSource product webpage