This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
RABBIT ANTI AIF (aa593-606)
catalog :
MBS221628
quantity :
0.1 mg
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
product information
catalog number :
MBS221628
products type :
Antibody
products full name :
RABBIT ANTI AIF (aa593-606)
products short name :
AIF
other names :
apoptosis-inducing factor 1, mitochondrial isoform 4; Apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor 1, mitochondrial; Neuropathy, axonal motor-sensory, with deafness and mental retardation; neuropathy, axonal, motor-sensory with deafness and mental retardation (Cowchock syndrome); programmed cell death 8 (apoptosis-inducing factor); striatal apoptosis-inducing factor; apoptosis-inducing factor, mitochondrion-associated, 1; Programmed cell death protein 8
products gene name :
AIF
other gene names :
AIFM1; AIFM1; AIF; CMT2D; CMTX4; COWCK; NADMR; NAMSD; PDCD8; COXPD6; AIF; PDCD8
uniprot entry name :
AIFM1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse, Rat
sequence length :
261
specificity :
This item recognises apoptosis inducing factor (AIF). The antibody reacts with the C-terminal region of the AIF. AIF is widely expressed in human tissues and localises in the mitochondria. AIF translocates to the nucleus upon induction of apoptosis.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 0.5 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Western Blot (WB)
other info1 :
Perservative Stabilisers: 0.02% Sodium Azide
other info2 :
Immunogen: Peptide corresponding to amino acids 593 - 606 of human AIF (CT). Buffer Solution: Phosphate buffered saline. Antiserum Preparation: Antisera to AIF (CT) were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human
products description :
MBS221628 recognises apoptosis inducing factor (AIF). The antibody reacts with the C-terminal region of the AIF. AIF is widely expressed in human tissues and localises in the mitochondria. AIF translocates to the nucleus upon induction of apoptosis.
ncbi gi num :
195927004
ncbi acc num :
NP_001124318.1
ncbi gb acc num :
NM_001130846.2
uniprot acc num :
O95831
ncbi mol weight :
26,033 Da
ncbi pathways :
Apoptosis Pathway 83060!!Apoptosis Pathway 470!!Apoptosis Modulation By HSP70 Pathway 198877!!Ceramide Signaling Pathway 138023
ncbi summary :
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, May 2010]
size :
0.1 mg
price :
320 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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