This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
RABBIT ANTI HUMAN XEDAR
catalog :
MBS221471
quantity :
0.1 mg
price :
360 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
catalog number :
MBS221471
products type :
Antibody
products full name :
RABBIT ANTI HUMAN XEDAR
products short name :
XEDAR
other names :
tumor necrosis factor receptor superfamily member 27 isoform 1; Tumor necrosis factor receptor superfamily member 27; tumor necrosis factor receptor superfamily member 27; EDA-A2 receptor; X-linked ectodysplasin-A2 receptor; tumor necrosis factor receptor superfamily member XEDAR; ectodysplasin A2 receptor; X-linked ectodysplasin-A2 receptor; EDA-A2 receptor
products gene name :
XEDAR
other gene names :
EDA2R; EDA2R; XEDAR; EDAA2R; EDA-A2R; TNFRSF27; TNFRSF27; XEDAR; EDA-A2 receptor
uniprot entry name :
TNR27_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
sequence length :
297
specificity :
This item detects human X-linked ectodermal dysplasia receptor (XEDAR), a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist; XEDAR-s and XEDAR-L, produced by alternative splicing.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Western Blot (WB)
app notes :
Western Blot: This item detects a band of approximately 33kDa in 293 cell lysates. Western Blotting: Minimum Dilution: 0.5; Maximum Dilution: 2.0ug/ml
other info1 :
Perservative Stabilisers: 0.02% Sodium Azide
other info2 :
Immunogen: Recombinant human XEDAR. Buffer Solution: Phosphate buffered saline. Antiserum Preparation: Antisera to XEDAR were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human
products description :
MBS221471 detects human X-linked ectodermal dysplasia receptor (XEDAR), a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist; XEDAR-s and XEDAR-L, produced by alternative splicing.
ncbi gi num :
314122209
ncbi acc num :
NP_001186616.1
ncbi gb acc num :
NM_001199687.2
uniprot acc num :
Q9HAV5
ncbi mol weight :
32,959 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460
ncbi summary :
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2011]
size :
0.1 mg
price :
360 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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