GOAT ANTI RXR ALPHA | MyBioSource MBS221408 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

GOAT ANTI RXR ALPHA

catalog :

MBS221408

quantity :

0.1 mg

price :

540 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, enzyme immunoassay

product information

catalog number :

MBS221408

products type :

Antibody

products full name :

GOAT ANTI RXR ALPHA

products short name :

RXR ALPHA

other names :

retinoic acid receptor RXR-alpha isoform c; Retinoic acid receptor RXR-alpha; retinoic acid receptor RXR-alpha; nuclear receptor subfamily 2 group B member 1; retinoid X nuclear receptor alpha; retinoid X receptor, alpha; Nuclear receptor subfamily 2 group B member 1; Retinoid X receptor alpha

products gene name :

RXR ALPHA

other gene names :

RXRA; RXRA; NR2B1; NR2B1

uniprot entry name :

RXRA_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Goat

reactivity :

Mouse (Expected from Sequence), Rat (Expected from Sequence)

sequence length :

365

specificity :

This item detects an epitope within the internal region of retinoid X receptor alpha (RXR alpha). RXR alpha is a 54kD member of the steroid/ thyroid receptor superfamily of transcriptional regulators, and is a nuclear receptor that mediates the biological effects of retinoids through its involvement in retinoic acid-mediated gene activation. RXR alpha regulates gene transcription by recruiting coactivators or corepressors to their promoter sequences. RXRs play important roles in multiple signalling pathways, including cell growth, differentiation, homeostasis, metabolism, and development. This item does not cross-react with either RXR beta or gamma.

form :

Purified. Purified IgG - liquid

concentration :

IgG concentration 0.5 mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

ELISA (EIA), Western Blot (WB)

app notes :

Western Blot: This item detects a band of approximately 55kDa in human epidermoid carcinoma A431 lysates. A minimum incubation time of 1 hour is recommended with this antibody. ELISA: Minimum Dilution: 1/15000; Maximum Dilution: 1/20000. Western Blotting: Minimum Dilution: 0.5; Maximum Dilution: 3ug/ml

other info1 :

Perservative Stabilisers: 0.02% Sodium Azide. 0.5% Bovine Serum Albumin

other info2 :

Immunogen: Peptide sequence CQVNSSLTSPTGRGSM corresponding to the internal region of RXR alpha (NP_002948). Buffer Solution: TRIS buffered saline. Antiserum Preparation: Antisera to human RXR alpha were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human

products description :

MBS221408 detects an epitope within the internal region of retinoid X receptor alpha (RXR alpha). RXR alpha is a 54kD member of the steroid/ thyroid receptor superfamily of transcriptional regulators, and is a nuclear receptor that mediates the biological effects of retinoids through its involvement in retinoic acid-mediated gene activation. RXR alpha regulates gene transcription by recruiting coactivators or corepressors to their promoter sequences. RXRs play important roles in multiple signalling pathways, including cell growth, differentiation, homeostasis, metabolism, and development. MBS221408 does not cross-react with either RXR beta or gamma.

ncbi gi num :

632794854

ncbi acc num :

NP_001278850.1

ncbi gb acc num :

NM_001291921.1

uniprot acc num :

P19793

ncbi mol weight :

41,060 Da

ncbi pathways :

Activation Of Gene Expression By SREBF (SREBP) Pathway 685552!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Adipogenesis Pathway 198832!!BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway 477138!!Bile Acid And Bile Salt Metabolism Pathway 106144!!Bile Secretion Pathway 193146!!Bile Secretion Pathway 193095!!Biological Oxidations Pathway 105698!!Circadian Clock Pathway 187173

ncbi summary :

Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]

size :

0.1 mg

price :

540 USD