catalog number :
MBS221344
products full name :
SHEEP ANTI 14-3-3 (pSer185)
products short name :
14-3-3
other names :
14-3-3 protein gamma; 14-3-3 protein gamma; Protein kinase C inhibitor protein 1; KCIP-1
products gene name :
14-3-3
other gene names :
YWHAG; KCIP-1
uniprot entry name :
1433G_SHEEP
reactivity :
Bovine, Human, Mammals (Expected from Sequence), Mouse, Rabbit, Rat
specificity :
This item recognises the 14-3-3 isoforms beta and zeta which are phosphorylated at serine 185. The members of the 14-3-3 family of proteins are highly conserved and are involved in multiple signalling pathways. The phosphorylated forms of beta and zeta 14-3-3 are found endogenously in brain tissue.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from the date of despatch.
tested application :
Western Blot (WB)*
app notes :
Western Blot: This item detects a band of approximately 30kDa. Western Blotting: Minimum Dilution: 1/100; Maximum Dilution: 1/300; Application Note: For the detection of phosphoproteins, serine phosphatase inhibitors such as 10mM Sodium Fluoride should be added to the sample buffer. Milk or other casein-based blocking solutions are not recommended as casein is a phosphoprotein and its use can result in high background.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
other info2 :
Immunogen: Synthetic peptide corresponding to 14-3-3 beta and zeta phosphorylated at serine 185.Peptide sequence: EILNSPEKAC. Antiserum Preparation: Antisera to Phosphorylated 14-3-3 were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Sheep
products description :
MBS221344 recognises the 14-3-3 isoforms beta and zeta which are phosphorylated at serine 185. The members of the 14-3-3 family of proteins are highly conserved and are involved in multiple signalling pathways. The phosphorylated forms of beta and zeta 14-3-3 are found endogenously in brain tissue.
ncbi mol weight :
18,000 Da