RABBIT ANTI RAT ARG VASOPRESSIN RECEPTOR | MyBioSource MBS221213 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

RABBIT ANTI RAT ARG VASOPRESSIN RECEPTOR

catalog :

MBS221213

quantity :

0.05 mg

price :

1150 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, cow

application :

western blot, ELISA, enzyme immunoassay

product information

catalog number :

MBS221213

products type :

Antibody

products full name :

RABBIT ANTI RAT ARG VASOPRESSIN RECEPTOR

products short name :

ARG VASOPRESSIN RECEPTOR

other names :

vasopressin V2 receptor; Vasopressin V2 receptor; vasopressin V2 receptor; AVPR V2; V2R; Vasopressin receptor V2; antidiuretic hormone receptor; renal-type arginine vasopressin receptor; arginine vasopressin receptor 2; AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor

other gene names :

Avpr2; Avpr2; V2R

uniprot entry name :

V2R_RAT

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Bovine (Expected from Sequence), Human (Expected from Sequence), Mouse (Expected from Sequence), Pig (Expected from Sequence)

sequence length :

371

specificity :

This product is specific for Arginine Vasopressin Receptor (AVPR-V2). The immunising peptide has no significant similarity with AVP V1a or V1b receptors.

form :

Purified. Purified IgG - liquid

concentration :

IgG concentration 1.0 mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

Immunohistology Frozen, ELISA (EIA), Western Blot (WB)

app notes :

Western Blot: A glycosylated band at approximately 62 kD is observed using membranes from rat inner medulla. N-Glycanase reduces the size of this band to 36 kD (deglycosylated form).

other info1 :

Perservative Stabilisers: 0.09% Sodium Azide (NaN3). 0.1% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography.

other info2 :

Immunogen: 21 amino acid peptide from the 3rd cytoplasmic domain of rat AVP-V2. Buffer Solution: Phosphate buffered saline . Target Species: Rat

products description :

This product is specific for Arginine Vasopressin Receptor (AVPR-V2). The immunising peptide has no significant similarity with AVP V1a or V1b receptors.

ncbi gi num :

9506415

ncbi acc num :

NP_062009.1

ncbi gb acc num :

NM_019136.1

uniprot acc num :

Q00788

ncbi mol weight :

40,749 Da

ncbi pathways :

Aquaporin-mediated Transport Pathway (1121433); Class A/1 (Rhodopsin-like Receptors) Pathway (1120714); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1122016); Disease Pathway (1121849); G Alpha (s) Signalling Events Pathway (1120744); GPCR Downstream Signaling Pathway (1120743); GPCR Ligand Binding Pathway (1120713); GPCRs, Class A Rhodopsin-like Pathway (198500); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1121989); Neuroactive Ligand-receptor Interaction Pathway (83445)

ncbi summary :

G-protein coupled receptor for arginine vasopressin; responsible for mediation of antidiuretic effect and changes in blood pressure [RGD, Feb 2006]

uniprot summary :

AVPR2: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption. Defects in AVPR2 are the cause of nephrogenic syndrome of inappropriate antidiuresis (NSIAD). This disorder is characterized by an inability to excrete a free water load, with inappropriately concentrated urine and resultant hyponatremia, hypoosmolarity, and natriuresis. Defects in AVPR2 are the cause of diabetes insipidus nephrogenic X-linked (XNDI); also known as diabetes insipidus nephrogenic type 1. XNDI is caused by the inability of the renal collecting ducts to absorb water in response to arginine vasopressin. It is characterized by excessive water drinking (polydypsia), excessive urine excretion (polyuria), persistent hypotonic urine, and hypokalemia. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Transporter; Transporter, aquaporin family. Cellular Component: integral to plasma membrane; integral to membrane; intracellular. Molecular Function: peptide hormone binding; vasopressin receptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; I-kappaB kinase/NF-kappaB cascade; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; response to cytokine stimulus; positive regulation of cell proliferation; positive regulation of vasoconstriction; interferon-gamma production; positive regulation of systemic arterial blood pressure; positive regulation of blood pressure; cellular response to hormone stimulus

size1 :

0.05 mg

price1 :

1150 USD