catalog number :
MBS221210
products full name :
RABBIT ANTI VASOACTIVE INTESTINAL PEPTIDE
products short name :
VASOACTIVE INTESTINAL PEPTIDE
other names :
VIP peptides isoform 1 preproprotein; VIP peptides; VIP peptides; prepro-VIP; vasoactive intestinal peptide; Peptide histidine valine 42
other gene names :
VIP; VIP; PHM27; VIP
uniprot entry name :
VIP_HUMAN
reactivity :
Bovine (Expected from Sequence), Dog (Expected from Sequence), Horse (Expected from Sequence), Mouse (Expected from Sequence), Pig (Expected from Sequence), Rat (Expected from Sequence), Rhesus Monkey (Expected from Sequence), Sheep (Expected from Sequenc
specificity :
This item is specific for vasoactive intestinal peptide, a secreted peptide that causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Paraffin
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G
other info2 :
Immunogen: Synthetic peptide corresponding to full-length mature vasoactive intestinal peptide conjugated to Keyhole Limpet Haemocyanin. Histology Positive Control Tissue: Human small bowel. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
MBS221210 is specific for vasoactive intestinal peptide, a secreted peptide that causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
ncbi acc num :
NP_003372.1
ncbi gb acc num :
NM_003381.3
ncbi mol weight :
19,082 Da
ncbi pathways :
G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014]
uniprot summary :
VIP: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. Belongs to the glucagon family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6q25. Cellular Component: cell soma; extracellular region. Molecular Function: neuropeptide hormone activity; protein binding; hormone activity. Biological Process: negative regulation of smooth muscle cell proliferation; mRNA stabilization; negative regulation of potassium ion transport; regulation of signal transduction; positive regulation of vasodilation; body fluid secretion; G-protein coupled receptor protein signaling pathway; regulation of protein localization; learning and/or memory; positive regulation of cell proliferation; positive regulation of protein catabolic process; positive regulation of endothelial cell proliferation; regulation of sensory perception of pain; negative regulation of apoptosis