catalog number :
MBS221041
products full name :
SHEEP ANTI HUMAN OREXIN A
products short name :
OREXIN A
other names :
orexin; Orexin; orexin; prepro-orexin; hypocretin (orexin) neuropeptide precursor; Hypocretin; Hcrt
other gene names :
HCRT; HCRT; OX; PPOX; NRCLP1; OX; PPORX; PPOX; Hcrt; Hcrt1; Hcrt2
uniprot entry name :
OREX_HUMAN
reactivity :
Bovine (Expected from Sequence), Chimpanzee (Expected from Sequence), Dog (Expected from Sequence), Horse (Expected from Sequence), Mouse (Expected from Sequence), Pig (Expected from Sequence), Rabbit (Expected from Sequence), Rat (Expected from Sequence)
specificity :
This item is specific for human orexin A, an excitatory neuropeptide linked to alertness and wakefulness in humans.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 5.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, ELISA (EIA), Immunohistology Paraffin
app notes :
ELISA: Minimum Dilution: 1/20; Maximum Dilution: 1/100
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography
other info2 :
Immunogen: Synthetic peptide, PLPDCCRQKTCSC, corresponding to amino acids 2-14 of human orexin A conjugated to KLH. Histology Positive Control Tissue: Hypothalamus. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
MBS221041 is specific for human orexin A, an excitatory neuropeptide linked to alertness and wakefulness in humans.
ncbi acc num :
NP_001515.1
ncbi gb acc num :
NM_001524.1
ncbi mol weight :
13,363 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1127664!!Disease Pathway 530764!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Metabolic Disorders Of Biological Oxidation Enzymes Pathway 1127637!!Orexin And Neuropeptides FF And QRFP Bind To Their Respective Receptors Pathway 106362!!Peptide Ligand-binding Receptors Pathway 106358
ncbi summary :
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010]