catalog number : 
MBS221029
products full name : 
RABBIT ANTI RAT NMDA RECEPTOR NR2A
products short name : 
NMDAR NR2A
other names : 
glutamate receptor ionotropic, NMDA 2A; Glutamate receptor ionotropic, NMDA 2A; glutamate receptor ionotropic, NMDA 2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor subunit 2A; glutamate [NMDA] receptor subunit epsilon-1; glutamate receptor, ionotropic, N-methyl D-aspartate 2A; Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; NR2A
products gene name : 
NMDA
other gene names : 
Grin2a; Grin2a; NR2A; GluN2A; NMDAR2A; GluN2A; NMDAR2A; NR2A
uniprot entry name : 
NMDE1_RAT
reactivity : 
Fish, Human, Mouse
form : 
Purified. Purified IgG - lyophilised
storage stability : 
Prior to reconstitution store at 4 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended.  Shelf Life: 12 months from date of reconstitution.
tested application : 
Immunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB)
app notes : 
Immunohistology - Frozen:  Minimum Dilution: 1/1,000; Maximum Dilution: 1/2,000;.  Western Blotting:  Minimum Dilution: 1/500; Maximum Dilution: 1/1,000
other info1 : 
Technical Advice: 3 ug will (under appropriate conditions) quantitatively immunoprecipitate all NMDAR2A in 200 ug of rat brain.  Reconstitution: Reconstitute with 50 ul of PBS. Preparation: Purified IgG prepared by affinity chromatography
other info2 : 
Histology Positive Control Tissue: Hippocampus. Buffer Solution: Ammonium bicarbonate.  Target Species: Rat
products description : 
Rabbit anti Rat NMDA Receptor NR2A antibody recognizes the NMDA (N-methyl-D-aspartate) receptor NMDAR2A subunit. NMDA receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
ncbi acc num : 
NP_036705.3
ncbi gb acc num : 
NM_012573.3
ncbi mol weight : 
165,469 Da
ncbi pathways : 
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway  1121188!!Alcoholism Pathway  585585!!Alcoholism Pathway  587116!!Alzheimer's Disease Pathway  83489!!Alzheimer's Disease Pathway  509!!Amphetamine Addiction Pathway  547642!!Amphetamine Addiction Pathway  550546!!Amyotrophic Lateral Sclerosis (ALS) Pathway  83491!!Amyotrophic Lateral Sclerosis (ALS) Pathway  511!!CREB Phosphorylation Through The Activation Of CaMKII Pathway  1121195
ncbi summary : 
may play a role in synaptic transmission, learning and memory [RGD, Feb 2006]