RABBIT ANTI MOUSE G PROTEIN ALPHA 0 | MyBioSource MBS220900 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

RABBIT ANTI MOUSE G PROTEIN ALPHA 0

catalog :

MBS220900

quantity :

1 mL

price :

375 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS220900

products type :

Antibody

products full name :

RABBIT ANTI MOUSE G PROTEIN ALPHA 0

products short name :

G PROTEIN ALPHA 0

other names :

guanine nucleotide-binding protein G(o) subunit alpha isoform B; Guanine nucleotide-binding protein G(o) subunit alpha; guanine nucleotide-binding protein G(o) subunit alpha; guanine nucleotide-binding protein G(o) subunit alpha; GTP-binding protein alpha-o subunit; Go alpha; guanine nucleotide binding protein, alpha O

other gene names :

Gnao1; Gnao1; Gnao; alphaO; Galphao; AW050213; Gna0; Gnao

uniprot entry name :

GNAO_MOUSE

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Drosophila

sequence length :

354

sequence :

{C-}A-N-N-L-R-G-C-G-L-Y

form :

Purified. Purified IgG - liquid

concentration :

IgG concentration 5.0 mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

ELISA (EIA), Western Blot (WB)*

app notes :

ELISA: Minimum Dilution: 1/500; Maximum Dilution: 1/1000;. Western Blotting: Application Note: This antibody detects band at 39 kDa when used under reducing conditions against rat brain.

other info1 :

Perservative Stabilisers: 0.09% Sodium Azide (NaN3). Preparation: Purified IgG prepared by affinity chromatography on Protein G

other info2 :

Buffer Solution: Phosphate buffered saline. Target Species: Mouse

products description :

Rabbit anti Mouse G Protein alpha 0 antibody recognizes the alpha subunit of murine Guanine nucleotide-binding protein G(o). Guanine nucleotide-binding protein G(o) is a 354 amino acid membrane associated protein of ~40kDa forming a heterotrimeric protein complex with beta and gamma subunits. Two isoforms of the alpha subunit are generated by alternative splicing with a single amino acid substitution in the immunogen sequence (a lysine for an asparagine at position 346), it is not known whether this substitution affects the binding to isoform 2. Rabbit anti Mouse G Protein alpha 0 antibody has been used successfully for the detection of G(o) in Drosophila by western blotting (Guo et al. 2011).

ncbi gi num :

164607137

ncbi acc num :

NP_001106855.1

ncbi gb acc num :

NM_001113384.1

uniprot acc num :

P18872

ncbi mol weight :

40,036 Da

ncbi pathways :

Alcoholism Pathway (585577); Alcoholism Pathway (587116); Ca2+ Pathway (1110569); Calcium Regulation In The Cardiac Cell Pathway (198327); Chagas Disease (American Trypanosomiasis) Pathway (147810); Chagas Disease (American Trypanosomiasis) Pathway (147795); Cholinergic Synapse Pathway (217717); Circadian Entrainment Pathway (698783); Circadian Entrainment Pathway (699872); Dopaminergic Synapse Pathway (469201)

uniprot summary :

G-alpha(o): Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14. Interacts with RGS14. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Belongs to the G-alpha family. G(i/o/t/z) subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: G protein; G protein, heterotrimeric alpha G((i/o/t/z)); G protein, heterotrimeric. Cellular Component: neuron projection; protein complex; membrane; dendrite; plasma membrane; heterotrimeric G-protein complex; intracellular; myelin sheath. Molecular Function: GTPase activity; corticotropin-releasing hormone receptor 1 binding; GTP binding; guanyl nucleotide binding; metal ion binding; nucleotide binding; GTPase activating protein binding; signal transducer activity; protein binding; mu-type opioid receptor binding; G-protein beta/gamma-subunit binding; protein complex binding; metabotropic serotonin receptor binding. Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; negative regulation of calcium ion transport; metabolic process; dopamine receptor signaling pathway; locomotory behavior; signal transduction; response to organic nitrogen; cellular process; regulation of heart contraction; positive regulation of GTPase activity; aging

size1 :

1 mL

price1 :

375 USD

more info or order :

MyBioSource product webpage