catalog number :
MBS220533
products full name :
RABBIT ANTI CLOSTRIDIUM DIFFICILE TOXIN A
products short name :
CLOSTRIDIUM DIFFICILE TOXIN A
other names :
Toxin A; Toxin A
other gene names :
toxA; tcdA
uniprot entry name :
TOXA_PEPDI
specificity :
This item is specific for Clostridium difficile Toxin A, a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 5.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G.
other info2 :
Immunogen: Synthetic peptide corresponding to the amino acids 2123 - 2132 of the native molecule conjugated to Keyhole limpet Haemocyanin.Peptide sequence: CTIDGKKYYFN. Buffer Solution: Phosphate buffered saline. Target Species: Bacterial
products description :
MBS220533 is specific for Clostridium difficile Toxin A, a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
ncbi mol weight :
308,056 Da