catalog number :
MBS220281
products full name :
RABBIT ANTI CHOLERA TOXIN BETA:FITC
products short name :
CHOLERA TOXIN
other names :
cholera enterotoxin subunit B; Cholera enterotoxin subunit B; cholera enterotoxin subunit B; Cholera enterotoxin B chain; Cholera enterotoxin gamma chain; Choleragenoid
other gene names :
VC1456; ctxB; toxB
uniprot entry name :
CHTB_VIBCH
form :
FITC. Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
concentration :
IgG concentration 4 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Immunoprecipitation (IP)
other info1 :
Perservative Stabilisers: 0.1% Sodium Azide (NaN3). 1% Bovine Serum Albumin
other info2 :
Immunogen: Purified choleragenoid. Buffer Solution: Phosphate buffered saline. Target Species: Bacterial
products description :
Rabbit anti cholera toxin beta antibody recognizes the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
ncbi acc num :
NP_231099.1
ncbi gb acc num :
NC_002505.1
ncbi mol weight :
13,957 Da
ncbi pathways :
Vibrio Cholerae Infection Pathway 3473!!Vibrio Cholerae Infection Pathway 513!!Vibrio Cholerae Pathogenic Cycle Pathway 3474!!Vibrio Cholerae Pathogenic Cycle Pathway 514