catalog number :
MBS219771
products full name :
RAT ANTI MOUSE RIG-I
products short name :
RIG-I
other names :
probable ATP-dependent RNA helicase DDX58; Probable ATP-dependent RNA helicase DDX58; probable ATP-dependent RNA helicase DDX58; DEAD box protein 58; DEAD-box protein 58; DEAD/H box polypeptide RIG-I; RIG-1; RIG-I-like receptor 1; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; RIG-I-like receptor 1; RLR-1; Retinoic acid-inducible gene 1 protein; RIG-1; Retinoic acid-inducible gene I protein; RIG-I
products gene name :
RIG-I
other gene names :
Ddx58; Ddx58; RIG-I; RLR-1; C330021E21; 6430573D20Rik; RLR-1; RIG-1; RIG-I
uniprot entry name :
DDX58_MOUSE
specificity :
This item recognises mouse Retinoic acid-inducible gene 1 protein, or RIG-I, also known as DEAD-box protein 58. RIG-I is a receptor found in the cytoplasm that recognises viral RNA from replicating viruses in infected cells. Upon activation with intracellular RNA, a cascade is triggered resulting in the activation of NF-kappa-B, and the eventual induction of antiviral cytokines such as IFN-beta and RANTES. RIG-I is essential for the production of interferons in response to RNA viruses and as such play a key role in innate immunity.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 0.5mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Western Blot (WB)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
MBS219771 recognises mouse Retinoic acid-inducible gene 1 protein, or RIG-I, also known as DEAD-box protein 58. RIG-I is a receptor found in the cytoplasm that recognises viral RNA from replicating viruses in infected cells. Upon activation with intracellular RNA, a cascade is triggered resulting in the activation of NF-kappa-B, and the eventual induction of antiviral cytokines such as IFN-beta and RANTES. RIG-I is essential for the production of interferons in response to RNA viruses and as such play a key role in innate immunity.
ncbi acc num :
NP_766277.3
ncbi gb acc num :
NM_172689.3
ncbi mol weight :
26,479 Da
ncbi pathways :
Cytosolic DNA-sensing Pathway 125146!!Cytosolic DNA-sensing Pathway 124833!!Epstein-Barr Virus Infection Pathway 585576!!Epstein-Barr Virus Infection Pathway 587115!!Hepatitis B Pathway 694729!!Hepatitis C Pathway 173974!!Hepatitis C Pathway 173907!!Herpes Simplex Infection Pathway 377874!!Herpes Simplex Infection Pathway 377865!!Immune System Pathway 1110668