product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
RAT ANTI MOUSE TREM-1
catalog :
MBS219711
quantity :
0.25 mg
price :
365 USD
clonality :
monoclonal
host :
rat
reactivity :
mouse
application :
western blot, flow cytometry, FACS, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS219711
products type :
Antibody
products full name :
RAT ANTI MOUSE TREM-1
products short name :
TREM-1
other names :
triggering receptor expressed on myeloid cells 1; Triggering receptor expressed on myeloid cells 1; triggering receptor expressed on myeloid cells 1; triggering receptor expressed in monocytes 1; triggering receptor expressed on myeloid cells 1; CD_antigen: CD354
products gene name :
TREM-1
other gene names :
Trem1; Trem1; TREM-1
uniprot entry name :
TREM1_MOUSE
clonality :
Monoclonal
isotype :
IgG2a
clone :
L5-B8.2A12.3A12
host :
Rat
sequence length :
230
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen*, Flow cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Immunohistology - Frozen: Application Note: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. MyBioSource recommends the use of acetone fixation for frozen sections. . Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/100
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: Mouse TREM-1 Fc fusion protein. Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Rat anti Mouse Trem-1 antibody, clone L5-B8.2A12.3A12 recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.
ncbi gi num :
10946760
ncbi acc num :
NP_067381.1
ncbi gb acc num :
NM_021406.5
uniprot acc num :
Q9JKE2
ncbi mol weight :
25,409 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway 1110059!!DAP12 Interactions Pathway 1110771!!Hemostasis Pathway 1110026!!Immune System Pathway 1110668!!Innate Immune System Pathway 1110697
size :
0.25 mg
price :
365 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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