antibody

MOUSE ANTI PIG SURFACTANT PROTEIN D

MBS219620

0.25 mg

440 USD

monoclonal

mouse

nonconjugated

1.7

western blot, immunocytochemistry

Antibody

MOUSE ANTI PIG SURFACTANT PROTEIN D

SURFACTANT PROTEIN D

pulmonary surfactant-associated protein D; Pulmonary surfactant-associated protein D; pulmonary surfactant-associated protein D; lung surfactant protein D; surfactant, pulmonary-associated protein D; Lung surfactant protein D

SFTPD; SFTPD; SP-D; PSP-D; PSP-D; SP-D

SFTPD_PIG

Monoclonal

IgG1

1.7

Mouse

378

This item detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.

Purified. Purified IgG - liquid

IgG concentration 1.0mg/ml

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

Immunohistology Frozen, Immunofluorescence (IF), Immunohistology Paraffin*, Western Blot (WB)

Western Blot: This item detects a band of approximately 138kDa. Immunohistology - Frozen: Minimum Dilution: 1ug/ml. Immunohistology - Paraffin: Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. TRIS/EDTA buffer pH8.0 is recommended for this purpose.

Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Purified porcine surfactant protein D. Histology Positive Control Tissue: Porcine lung tissue. Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of theP3X63Ag.8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Pig

MBS219620 detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.

47523028

NP_999275.1

NM_214110.1

Q9N1X4

37,986 Da

Phagosome Pathway (153902); Phagosome Pathway (153859)

0.25 mg

440 USD