catalog number :
MBS219582
products full name :
MOUSE ANTI HUMAN BETA 2 MICROGLOBULIN:HRP
products short name :
BETA 2 MICROGLOBULIN
other names :
beta-2-microglobulin; Beta-2-microglobulin; beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin; beta-2-microglobulin; N/A
other gene names :
B2M; B2M; N/A
uniprot entry name :
B2MG_HUMAN
form :
HRP. Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Immunohistology Paraffin
app notes :
ELISA: Minimum Dilution: 1/250; Maximum Dilution: 1/2500
other info1 :
Perservative Stabilisers: 0.01% Thiomersal. HRP Stabiliser. Preparation: Purified IgG prepared by affinity chromatography on Protein A from ascites
other info2 :
Immunogen: Purified isolated human B2-microglobulin. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human beta 2 Microglobulin antibody, clone B2M-01 recognizes native beta 2 microglobulin which is a component of MHC class I molecules, which are present on all nucleated cells. Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients. Also known as B2M, it has been suggested that this protein can be used as a prognostic marker for HIV infection.
ncbi acc num :
NP_004039.1
ncbi gb acc num :
NM_004048.2
ncbi mol weight :
13,715 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Amyloids Pathway 366238!!Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway 366163!!Antigen Processing And Presentation Pathway 83074!!Antigen Processing And Presentation Pathway 485!!Antigen Processing-Cross Presentation Pathway 477122!!Class I MHC Mediated Antigen Processing Presentation Pathway 366161!!Cytokine Signaling In Immune System Pathway 366171!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550
ncbi summary :
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]