catalog number :
MBS219561
products full name :
MOUSE ANTI RAT CD63
products short name :
CD63
other names :
CD63 antigen; CD63 antigen; CD63 antigen; mast cell antigen AD1; Cd63 molecule; Mast cell antigen AD1; CD_antigen: CD63
products gene name :
CD63
other gene names :
Cd63; Cd63
uniprot entry name :
CD63_RAT
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistology Paraffin, Western Blot (WB)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/200
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Histology Positive Control Tissue: Mast cells or basophils. Buffer Solution: Phosphate buffered saline. Target Species: Rat
products description :
Mouse anti Rat CD63 antibody, clone AD1 specifically recognizes rat CD63, an intracellular type-III lysosomal glycoprotein and member of the tetraspanin (TM4SF) family, which is translocated to the cell surface upon activation of platelets, and therefore a potential indicator of platelet activation. Rat CD63 is expressed on mast cells, and studies using clone AD1, have shown that it is located near to FcER1. Mouse anti Rat CD63 antibody, clone AD1 partially inhibits IgE-mediated histamine release (Kitani et al. 1991).
ncbi acc num :
NP_058821.1
ncbi gb acc num :
NM_017125.3
ncbi mol weight :
25,699 Da
ncbi pathways :
Hemostasis Pathway (1120520); Lysosome Pathway (98756); Lysosome Pathway (96865); Platelet Activation, Signaling And Aggregation Pathway (1120530); Platelet Degranulation Pathway (1120547); Proteoglycans In Cancer Pathway (782034); Proteoglycans In Cancer Pathway (782054); Response To Elevated Platelet Cytosolic Ca2+ Pathway (1120545)
ncbi summary :
human homolog facilitates endocytosis of H,K-ATPase beta-subunit; may play a role in protein trafficking [RGD, Feb 2006]