catalog number :
MBS219538
products full name :
HAMSTER ANTI MOUSE CD103
products short name :
CD103
other names :
integrin alpha-E isoform 1; Integrin alpha-E; integrin alpha-E; integrin alpha M290; integrin alpha E, epithelial-associated; Integrin alpha M290; CD_antigen: CD103Cleaved into the following 2 chains:Integrin alpha-E light chain; Integrin alpha-E heavy chain
products gene name :
CD103
other gene names :
Itgae; Itgae; CD103; aM290; alpha-E1; A530055J10; alpha-M290; N/A
uniprot entry name :
ITAE_MOUSE
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 0.5mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/20
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography
other info2 :
Immunogen: Mouse intestinal intraepithelial lymphocytes. Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Hamster anti Mouse CD103 antibody, clone 2E7 recognizes mouse CD103, otherwise known as Integrin alpha-E. CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule aEbeta7. This complex is sometimes referred to as CD103, though strictly speaking CD103 only refers to the alpha chain. The beta 7 subunit can also interact with other integrin alpha chains. The aEbeta7 complex is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells.Hamster anti Mouse CD103 antibody, clone 2E7 has been reported to also recognize the aEbeta7 complex.
ncbi acc num :
NP_032425.2
ncbi gb acc num :
NM_008399.2
ncbi mol weight :
128,906 Da
ncbi pathways :
Extracellular Matrix Organization Pathway 1110302!!Focal Adhesion Pathway 198353!!Integrin Cell Surface Interactions Pathway 1110318!!Integrin-mediated Cell Adhesion Pathway 198372!!Regulation Of Actin Cytoskeleton Pathway 83286!!Regulation Of Actin Cytoskeleton Pathway 500