catalog number :
MBS219474
products full name :
MOUSE ANTI CLOSTRIDIUM DIFFICILE TOXIN B
products short name :
CLOSTRIDIUM DIFFICILE TOXIN B
other names :
Toxin B; Toxin B
other gene names :
toxB; tcdB
uniprot entry name :
TOXB_PEPDI
specificity :
This item is specific for Clostridium difficile toxin B. No reaction is observed with toxin A. Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin B (TcdB) is a large exotoxin. Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease. Both toxins modifies the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 0.1mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA)
app notes :
ELISA: Minimum Dilution: 1/20; Maximum Dilution: 1/200
other info1 :
Perservative Stabilisers: 0.1% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Bacterial
products description :
MBS219474 is specific for Clostridium difficile toxin B. No reaction is observed with toxin A. Clostridium difficile isa gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin B (TcdB) is a large exotoxin. Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease. Both toxins modifies the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell.
ncbi mol weight :
269,712 Da