catalog number :
MBS219373
products full name :
MOUSE ANTI RAT CD80
products short name :
CD80
other names :
CD80; CD80; CD80
products gene name :
CD80
uniprot entry name :
O55202_RAT
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
other info2 :
Immunogen: HTLV-1 transformed Lewis-S1 cells. Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the P3U1 mouse myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Rat
products description :
Mouse anti Rat CD80, clone 3H5 specifically recognizes rat CD80, otherwise known as B7-1, a type I transmembrane glycoprotein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells. CD80 is a B cell activation antigen, which functions in the CD28-CD80/CD86 co-stimulatory pathway vital for T cell activation and proliferation. In contrast, the interaction of CD80 with CD152 has an inhibitory effect on T cell responses. Clone 3H5 has been shown to block the co-stimulatory activity of rat CD80.
ncbi mol weight :
36,298 Da