This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
HAMSTER ANTI MOUSE CD178:FITC
catalog :
MBS219358
quantity :
0.1 mg
price :
280 USD
clonality :
monoclonal
host :
hamsters
conjugate :
FITC
clone name :
MFL4
reactivity :
mouse
application :
flow cytometry, FACS
product information
catalog number :
MBS219358
products type :
Antibody
products full name :
HAMSTER ANTI MOUSE CD178:FITC
products short name :
CD178
other names :
tumor necrosis factor ligand superfamily member 6 isoform 1; Tumor necrosis factor ligand superfamily member 6; tumor necrosis factor ligand superfamily member 6; CD95 ligand; Fas antigen ligand; generalized lymphoproliferative disease; Fas ligand (TNF superfamily, member 6); CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble formAlternative name(s):Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL
products gene name :
CD178
other gene names :
Fasl; Faslg; gld; CD178; CD95L; Fas-L; Faslg; CD95-L; Tnfsf6; APT1LG1; Apt1lg1; Cd95l; Fasl; gld; Tnfsf6; CD95-L; Fas ligand; FasL; sFasL; APL; FasL ICD; SPA
uniprot entry name :
TNFL6_MOUSE
clonality :
Monoclonal
isotype :
IgG
clone :
MFL4
host :
Hamster
sequence length :
69
form :
FITC. Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
concentration :
IgG concentration 0.1mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR. Flow Cytometry: Minimum Dilution: Neat
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3). 1% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: B6 mouse FasL/BHK cells. Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Hamster anti Mouse CD178 antibody, clone MFL4 recognizes both mouse and rat CD178, otherwise known as Fas Ligand/ CD95L, a 40kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, expressed by activated T cells and NK cells, which can be induced on a variety of cells by radiation, heat shock, chemotherapeutic agents and viral infection. CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses. The binding of CD178 to its receptor CD95 (Fas), induces Fas-mediated apoptosis of target cells, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis. The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis. Hamster anti Mouse CD178 antibody, clone MFL4 is reported to block CD178/CD95 induced apoptosis.
ncbi gi num :
6753818
ncbi acc num :
NP_034307.1
ncbi gb acc num :
NM_010177.4
uniprot acc num :
P41047
ncbi mol weight :
8,040 Da
ncbi pathways :
African Trypanosomiasis Pathway 194387!!African Trypanosomiasis Pathway 194323!!Allograft Rejection Pathway 83316!!Allograft Rejection Pathway 535!!Apoptosis Pathway 198339!!Apoptosis Pathway 83257!!Apoptosis Pathway 470!!Apoptosis Pathway 1111498!!Apoptosis Signaling Pathway 522973!!Autoimmune Thyroid Disease Pathway 83314
size :
0.1 mg
price :
280 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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