catalog number :
MBS219339
products full name :
MOUSE ANTI HUMAN CD75s
products short name :
CD75s
other names :
beta-galactoside alpha-2,6-sialyltransferase 1 isoform a; Beta-galactoside alpha-2,6-sialyltransferase 1; beta-galactoside alpha-2,6-sialyltransferase 1; B-cell antigen CD75; CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; ST6Gal I; alpha 2,6-ST 1; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; B-cell antigen CD75; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1
products gene name :
CD75s
other gene names :
ST6GAL1; ST6GAL1; ST6N; SIAT1; ST6GalI; SIAT1; Alpha 2,6-ST 1; ST6GalI
uniprot entry name :
SIAT1_HUMAN
form :
Purified. Purified IgM - liquid
concentration :
IgM concentration 0.1mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Flow cytometry (FC/FACS), Immunohistology Paraffin*
app notes :
Immunohistology - Frozen: Minimum Dilution: 1/10; Maximum Dilution: 1/100;. Immunohistology - Paraffin: Application Note: This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase.
other info1 :
Perservative Stabilisers: 0.05% Sodium Azide
other info2 :
Immunogen: Human lymphocytes and SU-DHL4 cell line. Histology Positive Control Tissue: Human Tonsil. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD75s antibody, clone LN-1 recognizes the human CD75s cell surface antigen, an alpha2,6 - sialylated carbohydrate epitope expressed by mature B cells (especially germinal centre B cells), red blood cells and some epithelial cells.
ncbi acc num :
NP_003023.1
ncbi gb acc num :
NM_003032.2
ncbi mol weight :
20,764 Da
ncbi pathways :
Asparagine N-linked Glycosylation Pathway 161013!!Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway 161014!!Defective ALG1 Causes ALG1-CDG (CDG-1k) Pathway 1127605!!Defective ALG11 Causes ALG11-CDG (CDG-1p) Pathway 1127608!!Defective ALG12 Causes ALG12-CDG (CDG-1g) Pathway 1127601!!Defective ALG14 Causes Congenital Myasthenic Syndrome (ALG14-CMS) Pathway 1127613!!Defective ALG2 Causes ALG2-CDG (CDG-1i) Pathway 1127603!!Defective ALG3 Causes ALG3-CDG (CDG-1d) Pathway 1127599!!Defective ALG6 Causes ALG6-CDG (CDG-1c) Pathway 1127597!!Defective ALG8 Causes ALG8-CDG (CDG-1h) Pathway 1127602
ncbi summary :
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009]