MyBioSource

antibody

MOUSE ANTI HUMAN ADIPONECTIN

MBS219143

0.2 mg

375 USD

monoclonal

mouse

human

ELISA, enzyme immunoassay

MBS219143

Antibody

MOUSE ANTI HUMAN ADIPONECTIN

ADIPONECTIN

adiponectin; Adiponectin; adiponectin; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; gelatin-binding protein 28; adiponectin, C1Q and collagen domain containing; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; apM-1; Gelatin-binding protein

ADIPOQ; ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1; ACDC; ACRP30; APM1; GBP28; ACRP30; apM-1

ADIPO_HUMAN

Monoclonal

IgG2a

Adn36

Mouse

244

Purified. Purified IgG - liquid

IgG concentration 1.0mg/ml

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

ELISA (EIA)

Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

Buffer Solution: Phosphate buffered saline. Target Species: Human

Mouse anti Human Adiponectin antibody, clone Adn36 recognizes human adiponectin, also known as Acrp30, 30 kDa adipocyte complement-related protein, Adipocyte, C1q and collagen domain-containing protein or Gelatin-binding protein. Adiponectin is a 244 amino acid major adipokine secreted into the bloodstream from adipose tissue to modulate metabolism, including glucose regulation and fatty acid catabolism (UniProt: Q15848). Adiponectin circulates as three distinct oligomeric forms, trimers (LMW), hexamers (MMW) and dodecamers-octodecamers (HMW) with distinct functions in various target tissues (Wang et al. 2008). Adiponectin is involved in regulation of circulating glucose levels and in regulation of insulin sensitivity. Concentrations of adiponectin are reduced in obesity associated metabolic and vascular disorders (Fasshauer et al. 2004) in particular lower circulating levels of HMW adiponectin correleates with the appearance of type II diabetes and acts as a predictor for this condition (Zhu et al. 2010). Mouse anti human adiponectin antibody, clone Adn36 has been used successfully in the development of a sensitive sandwich ELISA in conjunction with mouse anti human adiponectin antibody, clone 5H7 as a detection reagent for the measurement of circulating levels of adiponectin in human serum.

295317372

NP_001171271.1

NM_001177800.1

Q15848

26,414 Da

AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Adipogenesis Pathway 198832!!Developmental Biology Pathway 477129!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862188!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862314!!PPAR Signaling Pathway 83042

This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]

0.2 mg

375 USD