catalog number :
MBS217356
products full name :
RAT ANTI MOUSE ABCA7
products short name :
ABCA7
other names :
ATP-binding cassette sub-family A member 7; ATP-binding cassette sub-family A member 7; ATP-binding cassette sub-family A member 7; ATP-binding cassette, sub-family A (ABC1), member 7
products gene name :
ABCA7
other gene names :
Abca7; Abca7; ABCX; Abc51
uniprot entry name :
ABCA7_MOUSE
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G
other info2 :
Immunogen: ABCA7 transfected HeLa cells. Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Rat anti Mouse ABCA7 antibody, clone 4A7-144.1 recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 7 (ABCA7). The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA7 is a member of the ABC-A sub-family, which is predominantly expressed in the thymus and in other immune and haematopoietic tissues. The exact physiological function of ABCA7 is unknown, although the molecule shows the highest homology to ABCA1 and may play a similar role in lipid homeostasis.
ncbi acc num :
NP_038878.1
ncbi gb acc num :
NM_013850.1
ncbi mol weight :
236,884 Da
ncbi pathways :
ABC Transporters Pathway 83232!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 1111270!!ABCA Transporters In Lipid Homeostasis Pathway 1111271!!Transmembrane Transport Of Small Molecules Pathway 1111269!!Phosphate Acquisition II Pathway 542835
ncbi summary :
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is widely expressed with highest detection in spleen and hematopoietic tissues. The function of this protein has not yet been determined; however, a related human protein is thought to play a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008]