MOUSE ANTI HUMAN MUCIN 2:FITC | MyBioSource MBS216981 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MOUSE ANTI HUMAN MUCIN 2:FITC

catalog :

MBS216981

quantity :

0.1 mg

price :

365 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

996/1

reactivity :

human

application :

flow cytometry, FACS

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS216981

products type :

Antibody

products full name :

MOUSE ANTI HUMAN MUCIN 2:FITC

products short name :

MUCIN 2

other names :

mucin-2; Mucin-2; mucin-2; intestinal mucin-2; mucin 2, intestinal/tracheal; mucin-like protein; mucin 2, oligomeric mucus/gel-forming; Intestinal mucin-2

products gene name :

MUCIN 2

other gene names :

MUC2; MUC2; MLP; SMUC; MUC-2; SMUC; MUC-2

uniprot entry name :

MUC2_HUMAN

clonality :

Monoclonal

isotype :

IgG1

clone :

996/1

host :

Mouse

sequence length :

5179

specificity :

MUCIN 2. Mouse anti Human Muccin 2 Antibody, clone 996/1 recognizes human Mucin 2 (MUC-2), and shows no cross-reactivity with MUC-1, MUC-3 or MUC-4. In tissue sections Mouse anti Human Mucin 2 antibody, clone 996/1 recognizes colon, liver, and prostate tissues strongly. The antibody recognizes malignant colonic mucosa as whell as normal mucosa.

form :

FITC. Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid

concentration :

IgG concentration 0.1 mg/ml

storage stability :

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

Flow cytometry (FC/FACS)*

app notes :

Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10; Application Note: Membrane permeabilization is required for this application. MyBioSource recommend the use of Leucoperm

other info1 :

Perservative Stabilisers: 0.09% Sodium Azide (NaN3). 1% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant. Immunogen: MUC-2 tandem repeat peptide.

other info2 :

Buffer Solution: Phosphate buffered saline. Target Species: Human. Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of a mouse NS0 myeloma cell line.

products description :

Mouse anti Human Mucin 2 antibody, clone 996/1 recognizes human Mucin 2 (MUC-2), and shows no cross-reactivity with MUC-1, MUC-3 or MUC-4. In tissue sections Mouse anti Human Mucin 2 antibody, clone 996/1 recognizes colon, liver and prostate tissues strongly. The antibody recognizes malignant colonic mucosa as well as normal mucosa.

ncbi gi num :

557129045

ncbi acc num :

NP_002448.3

ncbi gb acc num :

NM_002457.3

uniprot acc num :

Q02817

ncbi pathways :

Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Metabolism Of Proteins Pathway (106230); O-linked Glycosylation Pathway (1127679); O-linked Glycosylation Of Mucins Pathway (530747); Post-translational Protein Modification Pathway (161012); Termination Of O-glycan Biosynthesis Pathway (530748); Vibrio Cholerae Infection Pathway (83101); Vibrio Cholerae Infection Pathway (513)

ncbi summary :

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

uniprot summary :

MUC2: Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. Protein type: Secreted; Secreted, signal peptide; Extracellular matrix. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: Golgi lumen. Molecular Function: protein binding. Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; maintenance of gastrointestinal epithelium; post-translational protein modification

size1 :

0.1 mg

price1 :

365 USD

more info or order :

MyBioSource product webpage