product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD49b:Biotin
catalog :
MBS216553
quantity :
0.025 mg
price :
185 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS216553
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD49b:Biotin
products short name :
CD49b
other names :
integrin alpha-2; Integrin alpha-2; integrin alpha-2; CD49 antigen-like family member B; VLA2 receptor, alpha-2 subunit; collagen receptor; human platelet alloantigen system 5; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD_antigen: CD49b
products gene name :
CD49b
other gene names :
ITGA2; ITGA2; BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2; CD49B; GPIa
uniprot entry name :
ITA2_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
AK7
host :
Mouse
sequence length :
1181
form :
Biotin. Purified IgG conjugated to Biotin - liquid
concentration :
IgG concentration 0.1 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
other info2 :
Fusion Partners: Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD49b antibody, clone AK7 recognizes the integrin alpha 2 subunit, which is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, approximately 50% of monocytes and most adherent cell lines. Mouse anti Human CD49b antibody, clone AK7 inhibits cell attachment to collagen.
ncbi gi num :
116295258
ncbi acc num :
NP_002194.2
ncbi gb acc num :
NM_002203.3
uniprot acc num :
P17301
ncbi mol weight :
129,295 Da
ncbi pathways :
Arf6 Trafficking Events Pathway 137954!!Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Axon Guidance Pathway 105688!!CHL1 Interactions Pathway 161007!!CXCR4-mediated Signaling Events Pathway 137910!!Developmental Biology Pathway 477129!!Dilated Cardiomyopathy Pathway 121494!!Dilated Cardiomyopathy Pathway 121285
ncbi summary :
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
size :
0.025 mg
price :
185 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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