This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD103
catalog :
MBS216525
quantity :
0.025 mg
price :
140 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G5.1
reactivity :
human
application :
immunoprecipitation, flow cytometry, FACS
product information
catalog number :
MBS216525
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD103
products short name :
CD103
other names :
integrin alpha-E; Integrin alpha-E; integrin alpha-E; HML-1 antigen; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; integrin alpha-IEL; mucosal lymphocyte 1 antigen; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); HML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigen; CD_antigen: CD103Cleaved into the following 2 chains:Integrin alpha-E light chain; Integrin alpha-E heavy chain
products gene name :
CD103
other gene names :
ITGAE; ITGAE; CD103; HUMINAE
uniprot entry name :
ITAE_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
2G5.1
host :
Mouse
sequence length :
1179
specificity :
This item recognises the human CD103 cell surface antigen, also known as the alphaE integrin. This reacts with various subsets of human intra-epithelial lymphocytes:- 40% of lamina propria T-cells; 30% of mesenteric lymphoblasts and some lymphocytes from other mucosa. It recognises less than 0.1% bone marrow cells and less than 0.7% PBL.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen*, Flow cytometry (FC/FACS), Immunoprecipitation (IP)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 5 x 105 cells in 100ul. Immunohistology - Frozen: Minimum Dilution: 1/50; Maximum Dilution: 1/100; Application Note: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. MyBioSource recommends the use of acetone fixation for frozen sections. . Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. 0.5% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein A from ascites
other info2 :
Immunogen: Human Intestinal lymphocyte. Histology Positive Control Tissue: Intestine. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the NS1 mouse myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
MBS213119 recognises the human CD103 cell surface antigen, also known as the alphaE integrin. This reacts with various subsets of human intra-epithelial lymphocytes:- 40% of lamina propria T-cells; 30% of mesenteric lymphoblasts and some lymphocytes from other mucosa. It recognises less than 0.1% bone marrow cells and less than 0.7% PBL.
ncbi gi num :
148728188
ncbi acc num :
NP_002199.3
ncbi gb acc num :
NM_002208.4
uniprot acc num :
P38570
ncbi mol weight :
130,159 Da
ncbi pathways :
E-cadherin Signaling In The Nascent Adherens Junction Pathway 138005!!Extracellular Matrix Organization Pathway 576262!!Focal Adhesion Pathway 198795!!Integrin Cell Surface Interactions Pathway 106110!!Integrin-mediated Cell Adhesion Pathway 198816!!Regulation Of Actin Cytoskeleton Pathway 83089!!Regulation Of Actin Cytoskeleton Pathway 500
ncbi summary :
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]
size :
0.025 mg
price :
140 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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