MyBioSource

antibody

MOUSE ANTI HUMAN F-ACTIN

MBS216361

0.05 mg

280 USD

monoclonal

mouse

human

FACS, flow cytometry

MBS216361

Antibody

MOUSE ANTI HUMAN F-ACTIN

ACTIN F TYPE

actin, cytoplasmic 2; Actin, cytoplasmic 2; actin, cytoplasmic 2; cytoskeletal gamma-actin; epididymis luminal protein 176; actin gamma 1; Gamma-actinActin, cytoplasmic 2, N-terminally processed

ACTG1; ACTG1; ACT; ACTG; BRWS2; DFNA20; DFNA26; HEL-176; ACTG

ACTG_HUMAN

Monoclonal

IgM

NH3

Mouse

375

Purified. Purified IgM - liquid

IgM concentration 1.0 mg/ml

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

Immunohistology Frozen, Flow cytometry (FC/FACS)

Flow Cytometry: Maximum Dilution: 1 / 10

Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgM prepared from tissue culture supernatant

Immunogen: Human monocytes and U937 cell line. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human

Mouse anti Human F-Actin antibody, clone NH3 recognizes human Filamentous actin (F-actin). The antibody binds to the N-terminal region of actin, but not to the extreme N-terminal 40 amino acids. In tissue sections the antibody stains the cytoplasm of macrophages strongly, and gives granular, localised nuclear staining of all cell types.

316659409

NP_001186883.1

NM_001199954.1

41,793 Da

Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Axon Guidance Pathway 105688!!Bacterial Invasion Of Epithelial Cells Pathway 149807!!Bacterial Invasion Of Epithelial Cells Pathway 148661!!Developmental Biology Pathway 477129!!Dilated Cardiomyopathy Pathway 121494

Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]

0.05 mg

280 USD