product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN THYROGLOBULIN
catalog :
MBS216338
quantity :
0.2 mg
price :
375 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
enzyme immunoassay, ELISA
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS216338
products type :
Antibody
products full name :
MOUSE ANTI HUMAN THYROGLOBULIN
products short name :
THYROGLOBULIN
other names :
thyroglobulin; Thyroglobulin; thyroglobulin; thyroglobulin; N/A
other gene names :
TG; TG; TGN; AITD3; Tg
uniprot entry name :
THYG_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
5G4
host :
Mouse
sequence length :
2,711
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: Thyroglobulin from human thyroid gland. Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human Thyroglobulin antibody, clone 5G4 recognizes human thyroglobulin, a 660kDa homodimer produced by the thyroid gland, specifically in the thyrocytes, and stored within the follicular lumen. Thyroglobulin is the precursor of the iodated thyroid hormones thyroxine (T4) and triiodothyronine (T3). These hormones affect protein, fat and carbohydrate metabolism. Defects in thyroglobulin production can lead to goiter, and increased susceptibility to autoimmune thyroid type 3 diseases, such as Graves disease and Hashimoto thyroiditis. Mouse anti Human Thyroglobulin antibody, clone 5G4 does not interfere with anti-thyroglobulin autoantibodies.
ncbi gi num :
55770862
ncbi acc num :
NP_003226.4
ncbi gb acc num :
NM_003235.4
uniprot acc num :
P01266
ncbi mol weight :
298,383 Da
ncbi pathways :
Autoimmune Thyroid Disease Pathway 83121!!Autoimmune Thyroid Disease Pathway 533!!Thyroid Hormone Synthesis Pathway 835410!!Thyroid Hormone Synthesis Pathway 839541!!Thyroxine (Thyroid Hormone) Production Pathway 920992
ncbi summary :
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
size :
0.2 mg
price :
375 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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