product summary
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company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI RICIN A CHAIN
catalog :
MBS216335
quantity :
0.2 mg
price :
390 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
RA999
reactivity :
castor bean
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS216335
products type :
Antibody
products full name :
MOUSE ANTI RICIN A CHAIN
products short name :
RICIN
other names :
Ricin; Ricin; Ricin precursor; rRNA N-glycosidase
other gene names :
RCOM_2159910
uniprot entry name :
RICI_RICCO
clonality :
Monoclonal
isotype :
IgG1
clone :
RA999
host :
Mouse
sequence length :
576
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3) . Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: Full length Ricin A (RCA60) from Ricinus communis. Buffer Solution: Phosphate buffered saline. Target Species: Plants
products description :
Mouse anti Ricin A Chain antibody, clone RA999 recognizes the A chain of the ricin toxin (RCA60), a 60kDa glycoprotein. Mouse anti Ricin A Chain antibody, clone RA999 also cross-reacts with RCA120. The ricin toxin consists of two chains, A and B, covalently linked by a disulfide bond. The A chain acts as a glycosidase that removes an adenine residue from the 28S rRNA. The area from which the adenine is removed is essential for binding of elongation factors, destroying it leaves the ribosome inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, much faster than the cell can replace them, meaning that a single ricin A chain can kill a cell. The B chain binds to complex carbohydrates on the cell surface to facilitate entry of the A chain into the cell. Without the B chain, the A chain has very low toxicity.Ricin is easily extracted from the castor bean (Ricinus communis), and the lethal dose for humans is very small. It is toxic when inhaled, ingested or injected and there is no known antidote, although a vaccine has been developed. Treatment is symptomatic and supportive, with long term organ damage likely in survivors. The ease of extraction and distribution makes it a potential candidate for biological warfare although it is less stable than other agents, such as anthrax.
ncbi gi num :
255588578
ncbi acc num :
XP_002534649.1
ncbi gb acc num :
XM_002534603.1
uniprot acc num :
P02879
ncbi mol weight :
64,091 Da
size1 :
0.2 mg
price1 :
390 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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