catalog number :
MBS216323
products full name :
MOUSE ANTI HUMAN PAPILLOMAVIRUS 11 PROTEIN E7
products short name :
PAPILLOMAVIRUS 11 PROTEIN E7
other names :
Protein E7; Protein E7
uniprot entry name :
VE7_HPV11
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Perservative Stabilisers: 0.09% Sodium azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: Protein E7 from human papillomavirus 11. Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Viral
products description :
Mouse anti Human Papillomavirus 11 Protein E7 antibody, clone 711-66 recognizes the E7 protein of human papilloma virus 11. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Type 11 HPV is a low risk type that causes anogenital warts and is not linked with cervical cancer. In rare cases HPV-11 may cause respiratory papillomatosis, where warts form on the larynx or other areas of the respiratory tract. The viral protein E7 binds to Rb (retinoblastoma protein) and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. This binding is of much lower affinity than the high-risk HPV E7 proteins. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. Mouse anti Human Papillomavirus 11 Protein E7 antibody, clone 711-66 cross-reacts minimally with the E7 protein of HPV-16 and HPV-18.
ncbi mol weight :
10,889 Da