product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
RAT ANTI MOUSE CD123
catalog :
MBS215983
quantity :
0.025 mg
price :
140 USD
clonality :
monoclonal
host :
rat
reactivity :
mouse
application :
immunocytochemistry, flow cytometry, FACS
more info or order :
product information
catalog number :
MBS215983
products type :
Antibody
products full name :
RAT ANTI MOUSE CD123
products short name :
CD123
other names :
interleukin-3 receptor subunit alpha; Interleukin-3 receptor subunit alpha; interleukin-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL-3 receptor alpha chain; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; Il-3 alpha subunit; interleukin-3 receptor class II alpha chain; interleukin 3 receptor, alpha chain; Interleukin-3 receptor class II alpha chain; CD_antigen: CD123
products gene name :
CD123
other gene names :
Il3ra; Il3ra; CD123; SUT-1; CDw123; Sut-1; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA
uniprot entry name :
IL3RA_MOUSE
clonality :
Monoclonal
isotype :
IgG2a
clone :
5B11
host :
Rat
sequence length :
396
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS), Immunofluorescence (IF)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/50
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: CTLL cells transfected with mouse CD123. Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Rat anti Mouse CD123 antibody, clone 5B11 recognizes murine CD123, which is the 70kD alpha chain of the interleukin-3 receptor (IL-3R). CD123 is expressed on haematopoietic progenitors and most myeloid cells including basophils and mast cells. Certain mouse strains including A/J, AKR/J and NZB/B1NJ are reported to have low levels of CD123 expression due to aberrant splicing of the IL-3R alpha subunit gene. In mouse, CD123 can associate with either the common beta subunit CDw131 or with the murine IL-3 beta subunit to form a high affinity receptor for IL-3. IL-3 can bind to CD123 itself but with low affinity. Binding of IL-3 to the IL-3 receptor complex induces the proliferation and differentiation of haematopoietic cells. Rat anti Mouse CD123 antibody, clone 5B11 does not block the binding of IL-3 to the high affinity IL-3 receptor.
ncbi gi num :
6680429
ncbi acc num :
NP_032395.1
ncbi gb acc num :
NM_008369.1
uniprot acc num :
P26952
ncbi mol weight :
42,017 Da
ncbi pathways :
Apoptosis Pathway 83257!!Apoptosis Pathway 470!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Hematopoietic Cell Lineage Pathway 83275!!Hematopoietic Cell Lineage Pathway 489!!IL-3 Signaling Pathway 198420!!Jak-STAT Signaling Pathway 83274!!Jak-STAT Signaling Pathway 488!!PI3K-Akt Signaling Pathway 692242
size :
0.025 mg
price :
140 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!