MyBioSource

antibody

MOUSE ANTI SHEEP CD45:RPE

MBS215640

100 Tests

590 USD

monoclonal

mouse

PE

human

flow cytometry, FACS

MBS215640

Antibody

MOUSE ANTI SHEEP CD45:RPE

CD45

CD45, partial; Receptor-type tyrosine-protein phosphatase C; receptor-type tyrosine-protein phosphatase C; CD45 antigen; T200 glycoprotein; T200 leukocyte common antigen; protein tyrosine phosphatase, receptor type, c polypeptide; protein tyrosine phosphatase, receptor type, C; Leukocyte common antigen; L-CA; T200; CD_antigen: CD45

CD45

PTPRC; PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; CD45; L-CA

PTPRC_HUMAN

Monoclonal

IgG1

1.11.32

Mouse

72

Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised

Prior to reconstitution store at 4 degree C. Following reconstitution store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.

Flow cytometry (FC/FACS)

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Maximum Dilution: Neat

Reconstitution: Reconstitute with 1 ml distilled water. Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. 5% Sucrose. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Ovine efferent lymphatic duct lymphocytes. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS-1 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Sheep

Mouse anti Sheep CD45 antibody, clone 1.11.32 recognizes the ovine CD45 (Leucocyte common antigen), which is expressed on all ovine lymphocytes, macrophages and granulocytes. Mouse anti Sheep CD45 antibody, clone 1.11.32 immunoprecipitates CD45 molecules of 190kD, 210kDa and 225kDa from lymph node lysates.

44242008

AAS46946.1

130,898 Da

Adaptive Immune System Pathway 366160!!Axon Guidance Pathway 105688!!B Cell Receptor Signaling Pathway 198909!!BCR Signaling Pathway 138058!!CXCR4-mediated Signaling Events Pathway 137910!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Developmental Biology Pathway 477129!!EPO Receptor Signaling Pathway 198882!!Fc Gamma R-mediated Phagocytosis Pathway 114228

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

100 Tests

590 USD