This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CYTOCHROME P450 AROMATASE
catalog :
MBS215488
quantity :
1 ml
price :
750 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H4
reactivity :
human
application :
western blot, immunocytochemistry
product information
catalog number :
MBS215488
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CYTOCHROME P450 AROMATASE
products short name :
CYTOCHROME P450 AROMATASE
other names :
aromatase; Aromatase; aromatase; cytochrome P-450AROM; cytochrome P450 19A1; cytochrome P450, subfamily XIX (aromatization of androgens); estrogen synthase; estrogen synthetase; flavoprotein-linked monooxygenase; microsomal monooxygenase; cytochrome P450, family 19, subfamily A, polypeptide 1; CYPXIX; Cytochrome P-450AROM; Cytochrome P450 19A1; Estrogen synthase
other gene names :
CYP19A1; CYP19A1; ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM; ARO1; CYAR; CYP19
uniprot entry name :
CP19A_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
H4
host :
Mouse
sequence length :
503
form :
10 X Concentrate. Concentrated Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunofluorescence (IF), Immunohistology Paraffin, Western Blot (WB)
app notes :
Western Blot: This item detects a band of approximately 55KD in human placental extracts. Immunohistology: This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Western Blotting: Maximum Dilution: 1/250
other info1 :
Perservative Stabilisers: 0.1% Sodium Azide
other info2 :
Histology Positive Control Tissue: Human placenta. Target Species: Human
products description :
Mouse anti Human Cytochrome P450 Aromatase antibody, clone H4 recognizes a conserved epitope within cytochrome P450 aromatase (P450 arom). P450 arom plays an important role in estrogen biosynthesis and is highly conserved amongst mammals.P450 arom is highly expressed in placental tissue. For tissues where there may be low expression of P450 arom, the use of microsomal extracts may improve the staining for Western blots using Mouse anti Human Cytochrome P450 Aromatase antibody, clone H4 (Turner et al. 2002).
ncbi gi num :
13904858
ncbi acc num :
NP_000094.2
ncbi gb acc num :
NM_000103.3
uniprot acc num :
P11511
ncbi mol weight :
24,518 Da
ncbi pathways :
Biological Oxidations Pathway 105698!!C19/C18-Steroid Hormone Biosynthesis, Pregnenolone = Androstenedione = Estrone Pathway 413383!!C19/C18-Steroid Hormone Biosynthesis, Pregnenolone = Androstenedione = Estrone Pathway 468268!!Cytochrome P450 - Arranged By Substrate Type Pathway 105700!!Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway 1127640!!Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway 1127641!!Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway 1127642!!Defective CYP17A1 Causes Adrenal Hyperplasia 5 (AH5) Pathway 1127643!!Defective CYP19A1 Causes Aromatase Excess Syndrome (AEXS) Pathway 1127644!!Defective CYP1B1 Causes Glaucoma Pathway 1127645
ncbi summary :
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
size :
1 ml
price :
750 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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