MOUSE ANTI HUMAN CD97:APC | MyBioSource MBS215311 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MOUSE ANTI HUMAN CD97:APC

catalog :

MBS215311

quantity :

100 Tests

price :

440 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

MEM-180

reactivity :

human

application :

flow cytometry, FACS

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS215311

products type :

Antibody

products full name :

MOUSE ANTI HUMAN CD97:APC

products short name :

CD97

other names :

CD97 antigen isoform 3 preproprotein; CD97 antigen; CD97 antigen; leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; CD97 molecule; Leukocyte antigen CD97; CD_antigen: CD97Cleaved into the following 2 chains:CD97 antigen subunit alpha; CD97 antigen subunit beta

products gene name :

CD97

other gene names :

CD97; CD97; TM7LN1

uniprot entry name :

CD97_HUMAN

clonality :

Monoclonal

isotype :

IgG1

clone :

MEM-180

host :

Mouse

sequence length :

786

form :

APC. Purified IgG conjugated to Allophycocyanin (APC) - lyophilised

concentration :

IgG concentration 0.1mg/ml

storage stability :

Prior to reconstitution store at 4 degree C. After reconstitution store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of reconstitution.

tested application :

Flow cytometry (FC/FACS)

app notes :

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood . Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10

other info1 :

Reconstitution: Reconstitute with 1ml distilled water . Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein G

other info2 :

Buffer Solution: Phosphate buffered saline. Target Species: Human

products description :

Mouse anti Human CD97 antibody, clone MEM-180 recognizes the human CD97 cell surface antigen, a 74-89kDa glycoprotein expressed by granulocytes, monocytes, some activated lymphocytes and weakly by resting lymphocytes (5-15%). Mouse anti Human CD97 antibody, clone MEM-180 has been reported to detect CD97 antigen weakly in Western blotting.

ncbi gi num :

68508955

ncbi acc num :

NP_001020331.1

ncbi gb acc num :

NM_001025160.2

uniprot acc num :

P48960

ncbi mol weight :

86,628 Da

ncbi pathways :

Class B/2 (Secretin Family Receptors) Pathway (106378); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); GPCR Ligand Binding Pathway (161020); GPCRs, Class B Secretin-like Pathway (198781); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)

ncbi summary :

This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]

uniprot summary :

CD97: Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2. Chromosomal Location of Human Ortholog: 19p13.12. Cellular Component: extracellular space; focal adhesion; membrane; integral to plasma membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity; protein binding; transmembrane receptor activity; calcium ion binding. Biological Process: G-protein coupled receptor protein signaling pathway; cell surface receptor linked signal transduction; cell-cell signaling; immune response; cell adhesion; inflammatory response; cell motility

size1 :

100 Tests

price1 :

440 USD

more info or order :

MyBioSource product webpage